PMID- 21176197
OWN - NLM
STAT- MEDLINE
DCOM- 20110302
LR  - 20211020
IS  - 1475-2875 (Electronic)
IS  - 1475-2875 (Linking)
VI  - 9
DP  - 2010 Dec 22
TI  - Community response to intermittent preventive treatment of malaria in infants 
      (IPTi) in Papua New Guinea.
PG  - 369
LID - 10.1186/1475-2875-9-369 [doi]
AB  - BACKGROUND: Building on previous acceptability research undertaken in sub-Saharan 
      Africa this article aims to investigate the acceptability of intermittent 
      preventive treatment of malaria in infants (IPTi) in Papua New Guinea (PNG). 
      METHODS: A questionnaire was administered to mothers whose infants participated 
      in the randomised placebo controlled trial of IPTi. Mothers whose infants 
      participated and who refused to participate in the trial, health workers, 
      community reporters and opinion leaders were interviewed. Men and women from the 
      local community also participated in focus group discussions. RESULTS: 
      Respondents viewed IPTi as acceptable in light of wider concern for infant health 
      and the advantages of trial participation. Mothers reported complying with 
      at-home administration of IPTi due to perceived benefits of IPTi and pressure 
      from health workers. In spite of patchy knowledge, respondents also demonstrated 
      a demand for infant vaccinations and considered non-vaccination to be neglect. 
      There is little evidence that IPTi has negative impacts on attitudes to EPI, EPI 
      adherence or existing malaria prevention practices. CONCLUSION: The degree of 
      similarity between findings from the acceptability studies undertaken in 
      sub-Saharan Africa and PNG allows some generalization relating to the 
      implementation of IPTi outside of Africa: IPTi fits well with local health 
      cultures, appears to be accepted easily and has little impact on attitudes 
      towards EPI or malaria prevention. The study adds to the evidence indicating that 
      IPTi could be rolled out in a range of social and cultural contexts.
FAU - Pell, Christopher
AU  - Pell C
AD  - Barcelona Centre for International Health Research (CRESIB), Hospital Clinic / 
      IDIBAPS, Universitat de Barcelona, Spain.
FAU - Straus, Lianne
AU  - Straus L
FAU - Phuanukoonnon, Suparat
AU  - Phuanukoonnon S
FAU - Lupiwa, Sebeya
AU  - Lupiwa S
FAU - Mueller, Ivo
AU  - Mueller I
FAU - Senn, Nicolas
AU  - Senn N
FAU - Siba, Peter
AU  - Siba P
FAU - Gysels, Marjolein
AU  - Gysels M
FAU - Pool, Robert
AU  - Pool R
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20101222
PL  - England
TA  - Malar J
JT  - Malaria journal
JID - 101139802
RN  - 0 (Antimalarials)
RN  - 0 (Placebos)
SB  - IM
MH  - Antimalarials/*administration & dosage
MH  - Chemoprevention/*methods
MH  - Female
MH  - Humans
MH  - Infant
MH  - Interviews as Topic
MH  - Malaria/*prevention & control
MH  - Male
MH  - Papua New Guinea
MH  - Patient Acceptance of Health Care/*statistics & numerical data
MH  - Placebos/administration & dosage
MH  - Surveys and Questionnaires
PMC - PMC3224244
EDAT- 2010/12/24 06:00
MHDA- 2011/03/03 06:00
PMCR- 2010/12/22
CRDT- 2010/12/24 06:00
PHST- 2010/06/10 00:00 [received]
PHST- 2010/12/22 00:00 [accepted]
PHST- 2010/12/24 06:00 [entrez]
PHST- 2010/12/24 06:00 [pubmed]
PHST- 2011/03/03 06:00 [medline]
PHST- 2010/12/22 00:00 [pmc-release]
AID - 1475-2875-9-369 [pii]
AID - 10.1186/1475-2875-9-369 [doi]
PST - epublish
SO  - Malar J. 2010 Dec 22;9:369. doi: 10.1186/1475-2875-9-369.