PMID- 21185481
OWN - NLM
STAT- MEDLINE
DCOM- 20110503
LR  - 20220408
IS  - 1773-0430 (Electronic)
IS  - 0150-9918 (Linking)
VI  - 39
IP  - 8 Suppl 2
DP  - 2010 Dec
TI  - [Outcomes in women with history of gestational diabetes mellitus. Screening and 
      prevention of type 2 diabetes mellitus. Literature review].
PG  - S299-321
LID - 10.1016/S0368-2315(10)70056-9 [doi]
AB  - Women with a history of gestational diabetes mellitus (GDM) are characterized by 
      a high risk of type 2 diabetes mellitus (T2DM) (X 7), metabolic syndrome (X 2 to 
      5) and cardiovascular diseases (X 1,7). Women with lesser degrees of glucose 
      intolerance share the same risks. T2DM may occur from postpartum (5 to 14%) to 
      several years later, up to 25 years. Some factors associated with T2DM are 
      identified: obesity, early diagnostic before 24 weeks, high pregnancy OGTT blood 
      glucose or insulinotherapy. Screening for T2DM only with fasting glucose provides 
      less sensibility than with OGTT; HbA1c may supplant these dosages. The recurrence 
      rate of GDM is between 30 and 84%, non-white ethnicity and insulinotherapy during 
      GDM being the best proven predictors. High risk women need repeated life-long 
      screenings for glycemic abnomalies, or when another pregnancy is planned. Among 
      overweight or obese women with history of GDM who show minor glycoregulation 
      disturbances, it is proved that modifications of lifestyle in intensive programs 
      or metformin halve the risk of DT2. However, studies analysing practices show low 
      adhesion to screening; without an intensive program, few women implement 
      lifestyle modifications. These intensive programs should be implemented and 
      proposed to high-risk women. Their therapeutic education should also include 
      prevention of cardiovascular risk factors.
CI  - Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
FAU - Verier-Mine, O
AU  - Verier-Mine O
AD  - Service d'endocrinologie-diabetologie-obesite, Hopital Jean Bernard, Avenue 
      Desandrouin, BP479, 59322 Valenciennes Cedex, France. 
      veriermine-o@ch-valenciennes.fr
LA  - fre
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Devenir maternel apres un diabete gestationnel. Depistage et prevention du 
      diabete de type 2. Revue de la litterature.
PL  - France
TA  - J Gynecol Obstet Biol Reprod (Paris)
JT  - Journal de gynecologie, obstetrique et biologie de la reproduction
JID - 0322206
SB  - IM
MH  - Diabetes Mellitus, Type 2/*diagnosis/epidemiology/etiology/*prevention & control
MH  - *Diabetes, Gestational
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Pregnancy
MH  - Pregnancy Outcome
MH  - Risk Factors
EDAT- 2010/12/28 06:00
MHDA- 2011/05/04 06:00
CRDT- 2010/12/28 06:00
PHST- 2010/12/28 06:00 [entrez]
PHST- 2010/12/28 06:00 [pubmed]
PHST- 2011/05/04 06:00 [medline]
AID - S0368-2315(10)70056-9 [pii]
AID - 10.1016/S0368-2315(10)70056-9 [doi]
PST - ppublish
SO  - J Gynecol Obstet Biol Reprod (Paris). 2010 Dec;39(8 Suppl 2):S299-321. doi: 
      10.1016/S0368-2315(10)70056-9.