PMID- 21189055
OWN - NLM
STAT- MEDLINE
DCOM- 20110812
LR  - 20110415
IS  - 1651-2251 (Electronic)
IS  - 0001-6489 (Linking)
VI  - 131
IP  - 5
DP  - 2011 May
TI  - The specific IgE reactivity pattern of weed pollen-induced allergic rhinitis 
      patients.
PG  - 533-8
LID - 10.3109/00016489.2010.539265 [doi]
AB  - CONCLUSION: Specific immunoglobulin E (IgE) reactivity towards the major mugwort 
      allergen Art v 1 is a good indicator for Art v sensitization. Allergens from the 
      ragweed species Amb t and Amb a possibly share common IgE-binding epitopes. 
      OBJECTIVE: The aim of this study was to investigate the reactivity pattern of IgE 
      in Chinese patients with weed pollen-induced allergic rhinitis. METHODS: Sera 
      from 50 weed pollen-induced allergic rhinitis patients were tested for specific 
      serum IgE reactivity against allergenic extracts of mugwort (Artemisia vulgaris, 
      Art v), short ragweed (Ambrosia artemisiifolia, Amb a), giant ragweed (Ambrosia 
      trifida, Amb t), and single allergens of Art v 1, Art v 3, Amb a 1, and profilin. 
      RESULTS: Sera from 88% of the patients demonstrated positive specific IgE 
      reactivity to Art v, and of these 82% were positive to Art v 1. Sera from 38% of 
      the patients showed positive specific IgE reactivity to both ragweed species Amb 
      t and Amb a. A strong correlation was found between the specific IgE levels of 
      Amb t and Amb a. Of the Amb a IgE-positive patients, 38% were positive for Amb a 
      1. Of all patient sera tested, 12% were specific IgE-positive to profilin.
FAU - Han, Demin
AU  - Han D
AD  - Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, 
      Beijing Institute of Otolaryngology, Capital Medical University, No. 17 
      HouGouHuTong, Beijing, China.
FAU - Lai, Xuxin
AU  - Lai X
FAU - Gjesing, Birgitte
AU  - Gjesing B
FAU - Zhong, Nanshan
AU  - Zhong N
FAU - Zhang, Luo
AU  - Zhang L
FAU - Spangfort, Michael D
AU  - Spangfort MD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101228
PL  - England
TA  - Acta Otolaryngol
JT  - Acta oto-laryngologica
JID - 0370354
RN  - 0 (Amb a I protein, Ambrosia artemisiifolia)
RN  - 0 (Antigens, Plant)
RN  - 0 (Art v 1 protein, mugwort)
RN  - 0 (Art v 3 allergen, Artemisia vulgaris)
RN  - 0 (Plant Proteins)
RN  - 0 (Profilins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Ambrosia/*immunology
MH  - Antigens, Plant/immunology
MH  - Artemisia/*immunology
MH  - Child
MH  - China
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Middle Aged
MH  - Plant Proteins/immunology
MH  - Plant Weeds/*immunology
MH  - Pollen/*immunology
MH  - Profilins/immunology
MH  - Rhinitis, Allergic, Seasonal/blood/*immunology
MH  - Young Adult
EDAT- 2010/12/30 06:00
MHDA- 2011/08/13 06:00
CRDT- 2010/12/30 06:00
PHST- 2010/12/30 06:00 [entrez]
PHST- 2010/12/30 06:00 [pubmed]
PHST- 2011/08/13 06:00 [medline]
AID - 10.3109/00016489.2010.539265 [doi]
PST - ppublish
SO  - Acta Otolaryngol. 2011 May;131(5):533-8. doi: 10.3109/00016489.2010.539265. Epub 
      2010 Dec 28.