PMID- 21195489
OWN - NLM
STAT- MEDLINE
DCOM- 20130311
LR  - 20211020
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 157
IP  - 2
DP  - 2012 May 31
TI  - Duration of preceding hypertension is associated with prolonged length of ICU 
      stay.
PG  - 180-4
LID - 10.1016/j.ijcard.2010.12.011 [doi]
AB  - BACKGROUND: A substantial proportion of patients suffer prolonged length of 
      intensive care unit stay (PLOS) or prolonged mechanical ventilation (PMV) 
      following coronary artery bypass grafting (CABG). Identifying factors associated 
      with PLOS and PMV would aid in patient risk stratification. We sought to identify 
      the factors associated with PLOS and PMV following CABG. METHODS: Participants 
      were patients undergoing first-time elective CABG. All were observed until 
      discharge and clinical data were collected on a standardized proforma. PLOS and 
      PMV were defined a priori as >2 days and >12 h respectively, based on centre 
      norms. RESULTS: Of the 439 patients in the study, 105 (23.9%) had PLOS and 111 
      (25.2%) had PMV. Independent predictors of PMV were age, diabetes, previous 
      myocardial infarction (MI), New York Heart Association (NYHA) class and statin 
      use. The only independent predictor of PLOS was the duration of preceding 
      hypertension. CONCLUSION: The factors associated with PMV and PLOS in our study 
      are easily attainable, routine clinical details and may be built into bed 
      management algorithms. Confirmation of the association of preceding hypertension 
      and subsequent investigation of the possible mechanism mediating this 
      association, is suggested.
CI  - Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
FAU - Sanders, Julie S
AU  - Sanders JS
AD  - Department of Surgery and Interventional Science, University College London, 
      London, UK. j.sanders@ucl.ac.uk
FAU - Skipworth, James R A
AU  - Skipworth JR
FAU - Cooper, Jackie A
AU  - Cooper JA
FAU - Brull, David J
AU  - Brull DJ
FAU - Humphries, Steve E
AU  - Humphries SE
FAU - Mythen, Michael
AU  - Mythen M
FAU - Montgomery, Hugh E
AU  - Montgomery HE
LA  - eng
GR  - RG/08/008/25291/BHF_/British Heart Foundation/United Kingdom
GR  - PG 2008/14/BHF_/British Heart Foundation/United Kingdom
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101231
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Cohort Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypertension/*epidemiology/*therapy
MH  - Intensive Care Units/*trends
MH  - Length of Stay/*trends
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Respiration, Artificial/adverse effects/trends
MH  - Risk Factors
MH  - Time Factors
EDAT- 2011/01/05 06:00
MHDA- 2013/03/12 06:00
CRDT- 2011/01/04 06:00
PHST- 2010/05/02 00:00 [received]
PHST- 2010/10/11 00:00 [revised]
PHST- 2010/12/04 00:00 [accepted]
PHST- 2011/01/04 06:00 [entrez]
PHST- 2011/01/05 06:00 [pubmed]
PHST- 2013/03/12 06:00 [medline]
AID - S0167-5273(10)01052-1 [pii]
AID - 10.1016/j.ijcard.2010.12.011 [doi]
PST - ppublish
SO  - Int J Cardiol. 2012 May 31;157(2):180-4. doi: 10.1016/j.ijcard.2010.12.011. Epub 
      2010 Dec 31.