PMID- 21196879
OWN - NLM
STAT- MEDLINE
DCOM- 20120105
LR  - 20220331
IS  - 1698-6946 (Electronic)
IS  - 1698-4447 (Linking)
VI  - 16
IP  - 6
DP  - 2011 Sep 1
TI  - Lip squamous cell carcinoma in a Brazilian population: epidemiological study and 
      clinicopathological associations.
PG  - e757-62
AB  - OBJECTIVES: It was evaluated epidemiological aspects of primary lip squamous cell 
      carcinoma (LSCC) and its associations with clinicopathological factors. STUDY 
      DESIGN: This retrospective, cross-sectional study analysed a socio-demographic, 
      clinical, and morphological data of HNSCC in a Brazilian population (n=30). Data 
      analysis included descriptive statistics and bivariate analyses using the 
      chi-square and Fisher 's exact tests to compare the variables. RESULTS: The LSCC 
      represented 10.8% of all oral cavity squamous cell carcinoma. Lip malignant 
      disease was more prevalent in elderly men, with male-to-female ratio of 5:1. 
      Lower lip was more affected. It was observed high rates of chronic solar 
      exposure, and tobacco and alcohol drinking habits. Clinically, early TNM staging, 
      small tumour lesions, and non-metastatic disease were predominant findings. It 
      was identified a high frequency of well differentiated tumor samples. Worse 
      Karnofsky performance status was associated with cervical metastasis. 
      CONCLUSIONS: Our findings showed that LSCC patients exhibited similar 
      epidemiological and clinical profiles as noted in other studies. Still, the 
      occurrence of metastatic disease was associated with a worse physical performance 
      status of the LSCC patients during diagnosis.
FAU - Souza, R-L
AU  - Souza RL
AD  - Health Science Programme, State University of Montes Claros, Montes Claros, 
      Brazil.
FAU - Fonseca-Fonseca, T
AU  - Fonseca-Fonseca T
FAU - Oliveira-Santos, C-C
AU  - Oliveira-Santos CC
FAU - Correa, G-T-B
AU  - Correa GT
FAU - Santos, F-B-G
AU  - Santos FB
FAU - Cardoso, C-M
AU  - Cardoso CM
FAU - Sant' Ana-Haikal, D
AU  - Sant' Ana-Haikal D
FAU - Guimaraes, A-L-S
AU  - Guimaraes AL
FAU - Batista-De Paula, A-M-B
AU  - Batista-De Paula AM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110901
PL  - Spain
TA  - Med Oral Patol Oral Cir Bucal
JT  - Medicina oral, patologia oral y cirugia bucal
JID - 101231694
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Brazil
MH  - Carcinoma, Squamous Cell/*epidemiology/pathology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Lip Neoplasms/*epidemiology/pathology
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
EDAT- 2011/01/05 06:00
MHDA- 2012/01/06 06:00
CRDT- 2011/01/04 06:00
PHST- 2010/03/06 00:00 [received]
PHST- 2010/08/06 00:00 [accepted]
PHST- 2011/01/04 06:00 [entrez]
PHST- 2011/01/05 06:00 [pubmed]
PHST- 2012/01/06 06:00 [medline]
AID - 16954 [pii]
AID - 10.4317/medoral.16954 [doi]
PST - epublish
SO  - Med Oral Patol Oral Cir Bucal. 2011 Sep 1;16(6):e757-62. doi: 
      10.4317/medoral.16954.