PMID- 21210974
OWN - NLM
STAT- MEDLINE
DCOM- 20110414
LR  - 20211020
IS  - 1471-2164 (Electronic)
IS  - 1471-2164 (Linking)
VI  - 11 Suppl 5
IP  - Suppl 5
DP  - 2010 Dec 22
TI  - SIGLa: an adaptable LIMS for multiple laboratories.
PG  - S8
LID - 10.1186/1471-2164-11-S5-S8 [doi]
AB  - BACKGROUND: The need to manage large amounts of data is a clear demand for 
      laboratories nowadays. The use of Laboratory Information Management Systems 
      (LIMS) to achieve this is growing each day. A LIMS is a complex computational 
      system used to manage laboratory data with emphasis in quality assurance. Several 
      LIMS are available currently. However, most of them have proprietary code and are 
      commercialized with a high cost. Moreover, due to its complexity, LIMS are 
      usually designed to comply with the needs of one kind of laboratory, making it 
      very difficult to reuse a LIMS. In this work we describe the Sistema Integrado de 
      Gerencia de Laboratorios (SIGLa), an open source LIMS with a new approach 
      designed to allow it to adapt its activities and processes to various types of 
      laboratories. RESULTS: SIGLa incorporates a workflow management system, making it 
      possible to create and manage customized workflows. For each new laboratory a 
      workflow is defined with its activities, rules and procedures. During the 
      execution, for each workflow created, the values of attributes defined in a XPDL 
      file (which describe the workflow) are stored in SIGLa's database, allowing then 
      to be managed and retrieved upon request. These characteristics increase system's 
      flexibility and extend its usability to include the needs of multiple types of 
      laboratories. To construct the main functionalities of SIGLa a workflow of a 
      proteomic laboratory was first defined. To validate the SIGLa capability of 
      adapting to multiples laboratories, on this paper we study the process and the 
      needs of a microarray laboratory and define its workflow. This workflow has been 
      defined in a period of about two weeks, showing the efficiency and flexibility of 
      the tool. CONCLUSIONS: Using SIGLa it has been possible to construct a microarray 
      LIMS in a few days illustrating the flexibility and power of the method proposed. 
      With SIGLa's development we hope to contribute positively to the area of 
      management of complex data in laboratory by managing its large amounts of data, 
      guaranteeing the consistency of the data and increasing the laboratory 
      productivity. We also hope to make possible to laboratories with little resources 
      to afford a high level system for complex data management.
FAU - Melo, Alexandre
AU  - Melo A
AD  - Departamento de Ciencia da Computacao, Instituto de Ciencias Exatas Universidade 
      Federal de Minas Gerais, Av. Antonio Carlos, 6627 - Pampulha, Belo Horizonte, MG, 
      31270-901, Brazil. asmelo@dcc.ufmg.br
FAU - Faria-Campos, Alessandra
AU  - Faria-Campos A
FAU - DeLaat, Daiane Mariele
AU  - DeLaat DM
FAU - Keller, Rodrigo
AU  - Keller R
FAU - Abreu, Vinicius
AU  - Abreu V
FAU - Campos, Sergio
AU  - Campos S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20101222
PL  - England
TA  - BMC Genomics
JT  - BMC genomics
JID - 100965258
SB  - IM
MH  - *Clinical Laboratory Information Systems
MH  - Microarray Analysis/methods
MH  - Quality Assurance, Health Care
MH  - *Software
MH  - Workflow
PMC - PMC3045801
EDAT- 2011/01/19 06:00
MHDA- 2011/04/16 06:00
PMCR- 2010/12/22
CRDT- 2011/01/08 06:00
PHST- 2011/01/08 06:00 [entrez]
PHST- 2011/01/19 06:00 [pubmed]
PHST- 2011/04/16 06:00 [medline]
PHST- 2010/12/22 00:00 [pmc-release]
AID - 1471-2164-11-S5-S8 [pii]
AID - 10.1186/1471-2164-11-S5-S8 [doi]
PST - epublish
SO  - BMC Genomics. 2010 Dec 22;11 Suppl 5(Suppl 5):S8. doi: 
      10.1186/1471-2164-11-S5-S8.