PMID- 21211011
OWN - NLM
STAT- MEDLINE
DCOM- 20110502
LR  - 20240117
IS  - 1532-429X (Electronic)
IS  - 1097-6647 (Print)
IS  - 1097-6647 (Linking)
VI  - 13
IP  - 1
DP  - 2011 Jan 6
TI  - Prevalence and prognosis of myocardial scar in patients with known or suspected 
      coronary artery disease and normal wall motion.
PG  - 2
LID - 10.1186/1532-429X-13-2 [doi]
AB  - BACKGROUND: Some patients may have normal wall motion after myocardial 
      infarction. The aim of this study was to determine the prevalence and prognosis 
      of patients with myocardial scar in the absence of abnormal wall motion. We 
      studied patients with suspected or known coronary artery disease (CAD) who were 
      referred for cardiovascular magnetic resonance (CMR) for the assessment of global 
      and regional cardiac function and late gadolinium enhancement (LGE) and had 
      normal left ventricular wall motion. Prognostic value was determined by the 
      occurrence of hard endpoints (cardiac death and nonfatal myocardial infarction) 
      and major adverse cardiac events (MACE) which also included hospitalization due 
      to unstable angina or heart failure or life threatening ventricular arrhythmia. 
      RESULTS: A total 1148 patients (70.3%) were studied. LGE was detected in 104 
      patients (9.1%). Prevalence of LGE increased in patients with increased left 
      ventricular mass. Average follow-up time was 955 +/- 542 days. LGE was the 
      strongest predictor for hard endpoints and MACE. CONCLUSION: LGE was detected in 
      9.1% of patients with suspected or known CAD and normal wall motion. LGE was the 
      strongest predictor of significant cardiac events.
FAU - Krittayaphong, Rungroj
AU  - Krittayaphong R
AD  - Division of Cardiology, Department of Medicine, Siriraj Hospital, Mahidol 
      University, Bangkok, Thailand. sirkt@mahidol.ac.th
FAU - Saiviroonporn, Pairash
AU  - Saiviroonporn P
FAU - Boonyasirinant, Thananya
AU  - Boonyasirinant T
FAU - Udompunturak, Suthipol
AU  - Udompunturak S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20110106
PL  - England
TA  - J Cardiovasc Magn Reson
JT  - Journal of cardiovascular magnetic resonance : official journal of the Society 
      for Cardiovascular Magnetic Resonance
JID - 9815616
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Aged
MH  - Chi-Square Distribution
MH  - Cicatrix/*diagnosis/epidemiology
MH  - Cohort Studies
MH  - Coronary Angiography/methods
MH  - Coronary Artery Disease/*diagnosis/*epidemiology
MH  - Female
MH  - *Gadolinium
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/diagnosis/epidemiology
MH  - Myocardium/*pathology
MH  - Predictive Value of Tests
MH  - Prevalence
MH  - Prognosis
MH  - Proportional Hazards Models
MH  - Radiographic Image Enhancement/methods
MH  - Reference Values
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Survival Rate
MH  - Ventricular Function, Left/physiology
PMC - PMC3022594
EDAT- 2011/01/08 06:00
MHDA- 2011/05/03 06:00
PMCR- 2011/01/06
CRDT- 2011/01/08 06:00
PHST- 2010/08/31 00:00 [received]
PHST- 2011/01/06 00:00 [accepted]
PHST- 2011/01/08 06:00 [entrez]
PHST- 2011/01/08 06:00 [pubmed]
PHST- 2011/05/03 06:00 [medline]
PHST- 2011/01/06 00:00 [pmc-release]
AID - S1097-6647(23)01357-1 [pii]
AID - 1532-429X-13-2 [pii]
AID - 10.1186/1532-429X-13-2 [doi]
PST - epublish
SO  - J Cardiovasc Magn Reson. 2011 Jan 6;13(1):2. doi: 10.1186/1532-429X-13-2.