PMID- 21211196
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110107
IS  - 1009-3419 (Print)
IS  - 1009-3419 (Linking)
VI  - 7
IP  - 1
DP  - 2004 Feb 20
TI  - [Randomly clinical study of ITP and NP regimens in the treatment of non-small 
      cell lung cancer].
PG  - 64-6
LID - 10.3779/j.issn.1009-3419.2004.01.16 [doi]
AB  - BACKGROUND: To evaluate the efficacy and toxicity of ITP (ifosfamide + 
      perarubicin + cisplatin) and NP (vinorelbine + cisplatin) regimens in the 
      treatment of advanced non small cell lung cancer (NSCLC). METHODS: One hundred 
      inoperatable or recurrent patients with stage III and IV NSCLC were randomized 
      into ITP group and NP group treated by the two regimens responsively for 2 or 3 
      cycles. RESULTS: The overall response rate was 51.5% for ITP group and 50.9% for 
      the NP group, respectively. There was no statistically significant difference of 
      the overall response rate between the two groups ( P > 0.05). The major side 
      effects were leukopenia and gastrointestinal reaction. The leukopenia incidence 
      was higher in ITP group than that in NC group ( P < 0.05). CONCLUSIONS: Both ITP 
      and NP regimens are effective for the advanced NSCLC. Compared with ITP regimen, 
      NP regimen has less bone marrow toxicity than ITP regimen.
FAU - Yan, Xi
AU  - Yan X
AD  - Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan 
      University, Chengdu, Sichuan 610041, P.R.China.
FAU - Hou, Mei
AU  - Hou M
FAU - Gou, Hongfeng
AU  - Gou H
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Fei Ai Za Zhi
JT  - Zhongguo fei ai za zhi = Chinese journal of lung cancer
JID - 101126433
EDAT- 2004/02/20 00:00
MHDA- 2004/02/20 00:01
CRDT- 2011/01/08 06:00
PHST- 2011/01/08 06:00 [entrez]
PHST- 2004/02/20 00:00 [pubmed]
PHST- 2004/02/20 00:01 [medline]
AID - 10.3779/j.issn.1009-3419.2004.01.16 [doi]
PST - ppublish
SO  - Zhongguo Fei Ai Za Zhi. 2004 Feb 20;7(1):64-6. doi: 
      10.3779/j.issn.1009-3419.2004.01.16.