PMID- 21226707
OWN - NLM
STAT- MEDLINE
DCOM- 20110913
LR  - 20221207
IS  - 1365-2362 (Electronic)
IS  - 0014-2972 (Print)
IS  - 0014-2972 (Linking)
VI  - 41
IP  - 6
DP  - 2011 Jun
TI  - Coffee consumption is inversely associated with type 2 diabetes in Chinese.
PG  - 659-66
LID - 10.1111/j.1365-2362.2010.02455.x [doi]
AB  - BACKGROUND: Coffee consumption has been shown to be inversely associated to type 
      2 diabetes mellitus (T2DM), but evidence in Chinese populations is limited. We 
      investigated the relationship between coffee consumption and T2DM in a 
      population-based cohort of middle-aged Chinese. MATERIALS AND METHODS: We studied 
      2332 subjects who participated in the Taichung Community Health Study in Taiwan 
      in 2004. The relationships between coffee consumption, T2DM and fasting glucose 
      were assessed. RESULTS: The prevalence of T2DM was 14.0% and 10.4% in men and 
      women. After adjustment for age, body mass index, blood pressure, smoking, 
      alcohol drinking, betel nut chewing, physical activity, income, education level, 
      fat%, protein%, carbohydrate% and magnesium, coffee intake was inversely 
      associated with T2DM. Habitual coffee drinkers had 38-46% lower risk of T2DM than 
      nondrinkers. Compared to nondrinkers, the adjusted odds ratios (ORs) for T2DM 
      according to subjects with habitual coffee consumption (<1, 1-6, >/=7 times per 
      week) were 0.77 (0.52-1.13), 0.46 (0.28-0.76) and 0.37 (0.16-0.83), respectively. 
      The decreasing ORs indicate a dose-response effect of coffee consumption on the 
      likelihood of having T2DM (P<0.001). A similar relationship was also evident in 
      newly diagnosed T2DM (P<0.05). The adjusted mean fasting glucose levels gradually 
      decreased as the frequency of coffee consumption increased (P<0.05). CONCLUSIONS: 
      Coffee intake is inversely associated with T2DM in Chinese. Coffee may be a 
      protective agent for T2DM in Chinese.
CI  - (c) 2011 The Authors. European Journal of Clinical Investigation (c) 2011 Stichting 
      European Society for Clinical Investigation Journal Foundation.
FAU - Lin, Wen-Yuan
AU  - Lin WY
AD  - Department of Family Medicine, China Medical University Hospital, Taichung, 
      Taiwan.
FAU - Xaiver Pi-Sunyer, F
AU  - Xaiver Pi-Sunyer F
FAU - Chen, Ching-Chu
AU  - Chen CC
FAU - Davidson, Lance E
AU  - Davidson LE
FAU - Liu, Chiu-Shong
AU  - Liu CS
FAU - Li, Tsai-Chung
AU  - Li TC
FAU - Wu, Mei-Fong
AU  - Wu MF
FAU - Li, Chia-Ing
AU  - Li CI
FAU - Chen, Walter
AU  - Chen W
FAU - Lin, Cheng-Chieh
AU  - Lin CC
LA  - eng
GR  - DK 026687/DK/NIDDK NIH HHS/United States
GR  - P30 DK026687-26/DK/NIDDK NIH HHS/United States
GR  - P30 DK026687-30/DK/NIDDK NIH HHS/United States
GR  - P30 DK026687/DK/NIDDK NIH HHS/United States
GR  - P30 DK026687-29/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20110112
PL  - England
TA  - Eur J Clin Invest
JT  - European journal of clinical investigation
JID - 0245331
RN  - 0 (Blood Glucose)
RN  - 0 (Coffee)
SB  - IM
MH  - Aged
MH  - Asian People
MH  - Blood Glucose/*drug effects
MH  - *Coffee
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Dose-Response Relationship, Drug
MH  - Drinking Behavior
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Regression Analysis
MH  - Risk Factors
MH  - Socioeconomic Factors
MH  - Taiwan/epidemiology
PMC - PMC3087821
MID - NIHMS256389
COIS- Disclosure statement The authors declared no conflict of interest.
EDAT- 2011/01/14 06:00
MHDA- 2011/09/14 06:00
PMCR- 2012/06/01
CRDT- 2011/01/14 06:00
PHST- 2011/01/14 06:00 [entrez]
PHST- 2011/01/14 06:00 [pubmed]
PHST- 2011/09/14 06:00 [medline]
PHST- 2012/06/01 00:00 [pmc-release]
AID - 10.1111/j.1365-2362.2010.02455.x [doi]
PST - ppublish
SO  - Eur J Clin Invest. 2011 Jun;41(6):659-66. doi: 10.1111/j.1365-2362.2010.02455.x. 
      Epub 2011 Jan 12.