PMID- 21233786
OWN - NLM
STAT- MEDLINE
DCOM- 20111214
LR  - 20220321
IS  - 1539-2864 (Electronic)
IS  - 0275-004X (Linking)
VI  - 31
IP  - 7
DP  - 2011 Jul-Aug
TI  - Preoperative inner segment/outer segment junction in spectral-domain optical 
      coherence tomography as a prognostic factor in epiretinal membrane surgery.
PG  - 1366-72
LID - 10.1097/IAE.0b013e318203c156 [doi]
AB  - PURPOSE: To evaluate the macular structure on spectral-domain optical coherence 
      tomographic (SD-OCT) images to predict the outcome of surgery for idiopathic 
      epiretinal membrane. METHODS: Forty-five eyes of 45 consecutive patients with 
      idiopathic epiretinal membrane who had a preoperative visual acuity of </= 20/32 
      and were scheduled to undergo a transconjunctival 25-gauge vitrectomy were 
      involved in this prospective cohort study. The best-corrected visual acuity 
      (BCVA) and SD-OCT images of the fovea were examined before the surgery and at 3, 
      6, and 12 months after the surgery. Associations between the visual acuity 
      parameters and the preoperative SD-OCT features, including the morphology of the 
      photoreceptor inner segment/outer segment junction, macular thickness, 
      presence/absence of retinal cysts, and presence/absence of a macular pseudohole, 
      were investigated as predictors of the outcome of the surgery. The main outcome 
      measures were the association between the macular microstructure on preoperative 
      SD-OCT images and the visual acuity parameters, such as the BCVA, at 12 months 
      after the surgery (postoperative BCVA) and the difference between the 
      preoperative visual acuity and the postoperative BCVA. RESULTS: A total of 45 
      patients were enrolled in this study. The postoperative visual acuity was 
      significantly better for the eyes with an intact inner segment/outer segment 
      junction on the preoperative SD-OCT images than for those with an irregular or a 
      disrupted inner segment/outer segment junction on the images (P < 0.001). Better 
      preoperative visual acuity was associated with better visual acuity at 12 months 
      and a lesser degree of improvement in the visual acuity (P < 0.001, 
      respectively). CONCLUSION: The presence of an intact inner segment/outer segment 
      junction on the preoperative SD-OCT images was found to be an important predictor 
      of better visual recovery and better postoperative BCVA after epiretinal membrane 
      surgery.
FAU - Inoue, Maiko
AU  - Inoue M
AD  - Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, 
      Japan. maicoo@urahp.yokohama-cu.ac.jp
FAU - Morita, Satoshi
AU  - Morita S
FAU - Watanabe, Yoichiro
AU  - Watanabe Y
FAU - Kaneko, Tetsuji
AU  - Kaneko T
FAU - Yamane, Shin
AU  - Yamane S
FAU - Kobayashi, Satoshi
AU  - Kobayashi S
FAU - Arakawa, Akira
AU  - Arakawa A
FAU - Kadonosono, Kazuaki
AU  - Kadonosono K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Retina
JT  - Retina (Philadelphia, Pa.)
JID - 8309919
SB  - IM
MH  - Adult
MH  - Aged
MH  - Epiretinal Membrane/*diagnosis/physiopathology/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Preoperative Care
MH  - Prognosis
MH  - Retinal Photoreceptor Cell Inner Segment/*pathology
MH  - Retinal Photoreceptor Cell Outer Segment/*pathology
MH  - *Tomography, Optical Coherence
MH  - Visual Acuity/physiology
MH  - Vitrectomy
EDAT- 2011/01/15 06:00
MHDA- 2011/12/15 06:00
CRDT- 2011/01/15 06:00
PHST- 2011/01/15 06:00 [entrez]
PHST- 2011/01/15 06:00 [pubmed]
PHST- 2011/12/15 06:00 [medline]
AID - 10.1097/IAE.0b013e318203c156 [doi]
PST - ppublish
SO  - Retina. 2011 Jul-Aug;31(7):1366-72. doi: 10.1097/IAE.0b013e318203c156.