PMID- 21238751
OWN - NLM
STAT- MEDLINE
DCOM- 20110531
LR  - 20191210
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 83
IP  - 5
DP  - 2011 Feb 15
TI  - Pesticide residue analysis of fruit juices by LC-MS/MS direct injection. One year 
      pilot survey.
PG  - 1552-61
LID - 10.1016/j.talanta.2010.11.061 [doi]
AB  - For this work, thirteen types of fruit juices (orange, pineapple, peach, apple, 
      multifruit, mango, strawberry, tomato, pear, mandarin, grape, banana and 
      grapefruit) were selected to develop an analytical method for the analysis of 53 
      pesticides by direct injection in LC-MS/MS. The preparation of the samples was 
      very simple: an aliquot of the juice was centrifuged and it was ten-times diluted 
      prior to analysis, which allowed reducing considerably the time and cost of the 
      analyses. Besides, dilution of the samples permits reducing the amount of matrix 
      going into the system, and thus, decreasing the matrix effects, so common in this 
      type of commodities, opening the possibility to perform quantification with 
      solvent based standards. Validation of the method was carried out in accordance 
      with EU guidelines. Calibration curves covering three orders of magnitude were 
      performed, and they were linear over the concentration range studied for all the 
      matrices (from 0.1 to 100 mug L(-1)). Practical limits of quantification were in 
      the low mug L(-1) range, far below the maximum residue levels (MRLs) of the EU 
      regulations, which do not set specific MRLs for juices, and in this cases of 
      processed food, MRLs of the raw product are applied. Repeatability of the 
      instrumental method was studied in all matrices, obtaining good intra- and 
      inter-day relative standard deviations (RSDs). The proposed method was applied to 
      106 real fruit juice samples purchased in different local markets during a 
      one-year survey in order to validate the suitability for routine analysis. 43% of 
      the analysed samples gave positive results (higher than the practical limits of 
      quantification).
CI  - Copyright (c) 2010 Elsevier B.V. All rights reserved.
FAU - Ferrer, Carmen
AU  - Ferrer C
AD  - European Union Reference Laboratory (DG SANCO) for Residues of Pesticides in 
      Fruits and Vegetables, Department of Hydrogeology and Analytical Chemistry, 
      University of Almeria, Almeria, Spain. cferrer@ual.es
FAU - Martinez-Bueno, M J
AU  - Martinez-Bueno MJ
FAU - Lozano, Ana
AU  - Lozano A
FAU - Fernandez-Alba, A R
AU  - Fernandez-Alba AR
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20101202
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - *Beverages
MH  - Chromatography, Liquid/methods
MH  - Europe
MH  - Fruit/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Pilot Projects
MH  - Tandem Mass Spectrometry/methods
EDAT- 2011/01/18 06:00
MHDA- 2011/06/01 06:00
CRDT- 2011/01/18 06:00
PHST- 2010/08/05 00:00 [received]
PHST- 2010/11/03 00:00 [revised]
PHST- 2010/11/22 00:00 [accepted]
PHST- 2011/01/18 06:00 [entrez]
PHST- 2011/01/18 06:00 [pubmed]
PHST- 2011/06/01 06:00 [medline]
AID - S0039-9140(10)00941-0 [pii]
AID - 10.1016/j.talanta.2010.11.061 [doi]
PST - ppublish
SO  - Talanta. 2011 Feb 15;83(5):1552-61. doi: 10.1016/j.talanta.2010.11.061. Epub 2010 
      Dec 2.