PMID- 21245126 OWN - NLM STAT- MEDLINE DCOM- 20110707 LR - 20191210 IS - 1569-9285 (Electronic) IS - 1569-9285 (Linking) VI - 12 IP - 4 DP - 2011 Apr TI - Morphological and functional 3-Tesla magnetic resonance imaging of saphenous vein coronary artery bypass grafts. PG - 582-5 LID - 10.1510/icvts.2010.255026 [doi] AB - Evaluation of a novel non-invasive tool for postoperative follow-up of patients postelective saphenous vein coronary artery bypass graft (CABG) was performed. Ten patients were included. Their bypass grafts supplied the right coronary artery (7), marginal branches (1), diagonal branches (2), and the circumflex artery (n=1). Each bypass was examined intraoperatively using Doppler flow measurement. Patients were examined with a 3-Tesla magnetic resonance imaging (MRI) scanner (MAGNETOM Verio, Siemens, Erlangen, Germany) within one week postsurgery using MR-angiography with an intravasal contrast agent and velocity encoded phase-contrast flow measurements. Intraoperative Doppler flow measurements revealed regular flow patterns in all vascular territories supplied. The median intraoperative flow rate was 50 ml/min with an inter-quartile range (IQR) of 42-70 ml/min. The clinical postoperative course was uneventful. MRI showed all grafts to be patent. The median postoperative flow rate was 50 ml/min (IQR: 32-65 ml/min). MRI flow rates agreed well with intraoperative Doppler flow measurements (mean difference: -2.8+/-20.1 ml/min). This initial study demonstrates that 3-Tesla MRI flow measurements correlated well with Doppler thus reconfirming the graft patency postCABG. Further refinement and broader application of this technique may facilitate follow-up postCABG potentially replacing empiric clinical judgment by reliable non-invasive imaging. FAU - Hoppe, Hanno AU - Hoppe H AD - Department of Radiology, University Hospital Bern, Bern, Switzerland. FAU - Reineke, David AU - Reineke D FAU - Rosskopf, Andrea Bianca AU - Rosskopf AB FAU - Czerny, Martin AU - Czerny M FAU - Tevaearai, Hendrik AU - Tevaearai H FAU - Hess, Otto AU - Hess O FAU - Carrel, Thierry AU - Carrel T FAU - Ith, Michael AU - Ith M LA - eng PT - Evaluation Study PT - Journal Article DEP - 20110118 PL - England TA - Interact Cardiovasc Thorac Surg JT - Interactive cardiovascular and thoracic surgery JID - 101158399 RN - 0 (Contrast Media) RN - 0 (Organometallic Compounds) RN - AU0V1LM3JT (Gadolinium) RN - XM33Q67UVH (gadofosveset trisodium) SB - IM MH - Aged MH - Aged, 80 and over MH - Blood Flow Velocity MH - Contrast Media MH - *Coronary Artery Bypass/adverse effects MH - Coronary Circulation MH - Elective Surgical Procedures MH - Feasibility Studies MH - Gadolinium MH - Graft Occlusion, Vascular/*diagnosis/physiopathology MH - Humans MH - Laser-Doppler Flowmetry MH - *Magnetic Resonance Angiography MH - Male MH - Middle Aged MH - Organometallic Compounds MH - Pilot Projects MH - Predictive Value of Tests MH - Saphenous Vein/diagnostic imaging/pathology/physiopathology/*transplantation MH - Switzerland MH - Time Factors MH - Treatment Outcome MH - Ultrasonography MH - Vascular Patency EDAT- 2011/01/20 06:00 MHDA- 2011/07/08 06:00 CRDT- 2011/01/20 06:00 PHST- 2011/01/20 06:00 [entrez] PHST- 2011/01/20 06:00 [pubmed] PHST- 2011/07/08 06:00 [medline] AID - icvts.2010.255026 [pii] AID - 10.1510/icvts.2010.255026 [doi] PST - ppublish SO - Interact Cardiovasc Thorac Surg. 2011 Apr;12(4):582-5. doi: 10.1510/icvts.2010.255026. Epub 2011 Jan 18.