PMID- 21258521
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211020
IS  - 2156-7085 (Print)
IS  - 2156-7085 (Electronic)
IS  - 2156-7085 (Linking)
VI  - 1
IP  - 3
DP  - 2010 Sep 16
TI  - Swept-source based, single-shot, multi-detectable velocity range Doppler optical 
      coherence tomography.
PG  - 955-966
AB  - Phase-Resolved Doppler Optical Coherence Tomography (PR-DOCT) allows 
      visualization and characterization of the location, direction, velocity, and 
      profile of flow activity embedded in a static sample structure. The detectable 
      Velocity Dynamic Range (VDR) of each particular PR-DOCT system is governed by a 
      detectable Doppler phase shift, a flow angle, and an acquisition time interval 
      used to determine the Doppler phase shift. In general, the lower boundary of the 
      detectable Doppler phase shift is limited by the phase stability of the system, 
      while the upper boundary is limited by the pi phase ambiguity. For a given range 
      of detectable Doppler phase shift, shortening the acquisition duration will 
      increase not only the maximum detectable velocity but unfortunately also the 
      minimum detectable velocity, which may lead to the invisibility of a slow flow. 
      In this paper, we present an alternative acquisition scheme for PR-DOCT that 
      extends the lower limit of the velocity dynamic range, while maintaining the 
      maximum detectable velocity, hence increasing the overall VDR of PR-DOCT system. 
      The essence of the approach is to implement a technique of multi-scale 
      measurement to simultaneously acquire multiple VDRs in a single measurement. We 
      demonstrate an example of implementation of the technique in a dual VDR DOCT, 
      where two Doppler maps having different detectable VDRs were simultaneously 
      detected, processed, and displayed in real time. One was a fixed VDR DOCT capable 
      of measuring axial velocity of up to 10.9 mm/s without phase unwrapping. The 
      other was a variable VDR DOCT capable of adjusting its detectable VDR to reveal 
      slow flow information down to 11.3 mum/s. The technique is shown to effectively 
      extend the overall detectable VDR of the PR-DOCT system. Examples of real time 
      Doppler imaging of an African frog tadpole are demonstrated using the dual-VDR 
      DOCT system.
FAU - Meemon, Panomsak
AU  - Meemon P
FAU - Rolland, Jannick P
AU  - Rolland JP
LA  - eng
PT  - Journal Article
DEP - 20100916
PL  - United States
TA  - Biomed Opt Express
JT  - Biomedical optics express
JID - 101540630
PMC - PMC3018058
EDAT- 2011/01/25 06:00
MHDA- 2011/01/25 06:01
PMCR- 2010/09/16
CRDT- 2011/01/25 06:00
PHST- 2010/07/22 00:00 [received]
PHST- 2010/09/09 00:00 [revised]
PHST- 2010/09/14 00:00 [accepted]
PHST- 2011/01/25 06:00 [entrez]
PHST- 2011/01/25 06:00 [pubmed]
PHST- 2011/01/25 06:01 [medline]
PHST- 2010/09/16 00:00 [pmc-release]
AID - 132163 [pii]
AID - 10.1364/BOE.1.000955 [doi]
PST - epublish
SO  - Biomed Opt Express. 2010 Sep 16;1(3):955-966. doi: 10.1364/BOE.1.000955.