PMID- 21259024 OWN - NLM STAT- MEDLINE DCOM- 20120104 LR - 20211020 IS - 1439-6327 (Electronic) IS - 1439-6319 (Linking) VI - 111 IP - 9 DP - 2011 Sep TI - Combined carbohydrate-protein supplementation improves competitive endurance exercise performance in the heat. PG - 2051-61 LID - 10.1007/s00421-011-1831-5 [doi] AB - Laboratory-based studies have demonstrated that adding protein (PRO) to a carbohydrate (CHO) supplement can improve thermoregulatory capacity, exercise performance and recovery. However, no study has investigated these effects in a competitive sporting context. This study assessed the effects of combined CHO-PRO supplementation on physiological responses and exercise performance during 8 days of strenuous competition in a hot environment. Twenty-eight cyclists participating in the TransAlp mountain bike race were randomly assigned to fitness-matched placebo (PLA 76 g L(-1) CHO) or CHO-PRO (18 g L(-1) PRO, 72 g L(-1) CHO) groups. Participants were given enough supplements to allow ad libitum consumption. Physiological and anthropometric variables were recorded pre- and post-exercise. Body mass decreased significantly from race stage 1 to 8 in the PLA group (-0.75 +/- 0.22 kg, P = 0.01) but did not change in the CHO-PRO group (0.42 +/- 0.42 kg, P = 0.35). Creatine kinase concentration and muscle soreness were substantially elevated during the race, but were not different between groups (P = 0.82, P = 0.44, respectively). Urine osmolality was significantly higher in the CHO-PRO versus the PLA group (P = 0.04) and the rise in tympanic temperature from pre- to post-exercise was significantly less in CHO-PRO versus PLA (P = 0.01). The CHO-PRO group also completed the 8 stages significantly quicker than the PLA group (2,277 +/- 127 vs. 2,592 +/- 68 min, respectively, P = 0.02). CHO-PRO supplementation therefore appears to prevent body mass loss, enhance thermoregulatory capacity and improve competitive exercise performance despite no effect on muscle damage. FAU - Cathcart, Andrew J AU - Cathcart AJ AD - Institute for Diet, Exercise and Lifestyle, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK. FAU - Murgatroyd, Scott R AU - Murgatroyd SR FAU - McNab, Alison AU - McNab A FAU - Whyte, Laura J AU - Whyte LJ FAU - Easton, Chris AU - Easton C LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20110123 PL - Germany TA - Eur J Appl Physiol JT - European journal of applied physiology JID - 100954790 RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Proteins) RN - 0 (Drug Combinations) SB - IM MH - Adaptation, Physiological/drug effects/physiology MH - Adult MH - Athletic Performance/*physiology MH - Bicycling/physiology MH - Body Temperature Regulation/drug effects/physiology MH - Competitive Behavior/*drug effects/physiology MH - Dietary Carbohydrates/administration & dosage/*pharmacology MH - Dietary Proteins/administration & dosage/*pharmacology MH - Dietary Supplements MH - Drug Combinations MH - Female MH - *Hot Temperature/adverse effects MH - Humans MH - Male MH - Off-Road Motor Vehicles MH - Physical Endurance/*drug effects/physiology EDAT- 2011/01/25 06:00 MHDA- 2012/01/05 06:00 CRDT- 2011/01/25 06:00 PHST- 2010/05/07 00:00 [received] PHST- 2011/01/07 00:00 [accepted] PHST- 2011/01/25 06:00 [entrez] PHST- 2011/01/25 06:00 [pubmed] PHST- 2012/01/05 06:00 [medline] AID - 10.1007/s00421-011-1831-5 [doi] PST - ppublish SO - Eur J Appl Physiol. 2011 Sep;111(9):2051-61. doi: 10.1007/s00421-011-1831-5. Epub 2011 Jan 23.