PMID- 21261410
OWN - NLM
STAT- MEDLINE
DCOM- 20110719
LR  - 20220409
IS  - 1930-7810 (Electronic)
IS  - 0278-6133 (Print)
IS  - 0278-6133 (Linking)
VI  - 30
IP  - 2
DP  - 2011 Mar
TI  - Neural activity during health messaging predicts reductions in smoking above and 
      beyond self-report.
PG  - 177-85
LID - 10.1037/a0022259 [doi]
AB  - OBJECTIVE: The current study tested whether neural activity in response to 
      messages designed to help smokers quit could predict smoking reduction, above and 
      beyond self-report. DESIGN: Using neural activity in an a priori region of 
      interest (a subregion of medial prefrontal cortex [MPFC]), in response to ads 
      designed to help smokers quit smoking, we prospectively predicted reductions in 
      smoking in a community sample of smokers (N = 28) who were attempting to quit 
      smoking. Smoking was assessed via expired carbon monoxide (CO; a biological 
      measure of recent smoking) at baseline and 1 month following exposure to 
      professionally developed quitting ads. RESULTS: A positive relationship was 
      observed between activity in the MPFC region of interest and successful quitting 
      (increased activity in MPFC was associated with a greater decrease in expired 
      CO). The addition of neural activity to a model predicting changes in CO from 
      self-reported intentions, self-efficacy, and ability to relate to the messages 
      significantly improved model fit, doubling the variance explained (R(2)self-report 
      = .15, R(2)self-report + neural activity = .35, R(2)change = .20). CONCLUSION: Neural 
      activity is a useful complement to existing self-report measures. In this 
      investigation, we extend prior work predicting behavior change based on neural 
      activity in response to persuasive media to an important health domain and 
      discuss potential psychological interpretations of the brain-behavior link. Our 
      results support a novel use of neuroimaging technology for understanding the 
      psychology of behavior change and facilitating health promotion.
CI  - (c) 2011 APA, all rights reserved
FAU - Falk, Emily B
AU  - Falk EB
AD  - Department of Communication Studies, Research Center for Group Dynamics/Institute 
      for Social Research, University of Michigan, Ann Arbor, MI 48109, USA. 
      ebfalk@umich.edu
FAU - Berkman, Elliot T
AU  - Berkman ET
FAU - Whalen, Danielle
AU  - Whalen D
FAU - Lieberman, Matthew D
AU  - Lieberman MD
LA  - eng
GR  - F31 DA024904/DA/NIDA NIH HHS/United States
GR  - F31 DA024904-02/DA/NIDA NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Health Psychol
JT  - Health psychology : official journal of the Division of Health Psychology, 
      American Psychological Association
JID - 8211523
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - *Persuasive Communication
MH  - *Self Report
MH  - Smoking Cessation/*psychology
MH  - Synaptic Transmission/*physiology
PMC - PMC3059382
MID - NIHMS268183
EDAT- 2011/01/26 06:00
MHDA- 2011/07/20 06:00
PMCR- 2011/03/17
CRDT- 2011/01/26 06:00
PHST- 2011/01/26 06:00 [entrez]
PHST- 2011/01/26 06:00 [pubmed]
PHST- 2011/07/20 06:00 [medline]
PHST- 2011/03/17 00:00 [pmc-release]
AID - 2011-01122-001 [pii]
AID - 10.1037/a0022259 [doi]
PST - ppublish
SO  - Health Psychol. 2011 Mar;30(2):177-85. doi: 10.1037/a0022259.