PMID- 21263736 OWN - NLM STAT- MEDLINE DCOM- 20110504 LR - 20191210 IS - 1539-4522 (Electronic) IS - 1559-128X (Linking) VI - 50 IP - 3 DP - 2011 Jan 20 TI - Evaluation of spectrometric parameters in spectral-domain optical coherence tomography. PG - 366-72 LID - 10.1364/AO.50.000366 [doi] AB - The parameters of the spectrometer were analyzed in order to optimize the performance of spectral-domain optical coherence tomography (SD-OCT). Because probing depth is proportional to spectral resolution, it can be increased with the choice of a higher resolution spectrometer, which implies greater pixel numbers and lower imaging speed, or by sacrificing part of the spectrum, which compromises the axial resolution and side lobes. With a dynamic range of 8 bits or more, the signal-to-noise ratio remains constant for different noise levels. The results were verified experimentally with in vivo retinal SD-OCT imaging. FAU - Xi, Peng AU - Xi P AD - Department of Biomedical Engineering, College of Engineering, Peking University, No. 5 Yiheyuan Road, Beijing 100871, China. xipeng@coe.pku.edu.cn FAU - Mei, Kai AU - Mei K FAU - Brauler, Tobias AU - Brauler T FAU - Zhou, Chuanqing AU - Zhou C FAU - Ren, Qiushi AU - Ren Q LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Appl Opt JT - Applied optics JID - 0247660 SB - IM MH - Computer Simulation MH - Humans MH - Image Processing, Computer-Assisted/methods MH - Retina/*ultrastructure MH - Spectrum Analysis MH - Tomography, Optical Coherence/instrumentation/*methods EDAT- 2011/01/26 06:00 MHDA- 2011/05/05 06:00 CRDT- 2011/01/26 06:00 PHST- 2011/01/26 06:00 [entrez] PHST- 2011/01/26 06:00 [pubmed] PHST- 2011/05/05 06:00 [medline] AID - 209519 [pii] AID - 10.1364/AO.50.000366 [doi] PST - ppublish SO - Appl Opt. 2011 Jan 20;50(3):366-72. doi: 10.1364/AO.50.000366.