PMID- 21268449 OWN - NLM STAT- MEDLINE DCOM- 20110218 LR - 20191112 IS - 0048-7554 (Print) IS - 0048-7554 (Linking) VI - 25 IP - 4 DP - 2010 Oct-Dec TI - Synergistic ecotoxicity of APEOs-PAHs in rivers and sediments: is there a potential health risk? PG - 351-7 AB - The occurrence and persistence of anthropogenic pollutants in the environment showing estrogenic-endocrine modulating effects in aquatic organisms is a 'hot' issue of major health- and environment-related concern worldwide. The population growth and the increasing scarcity of water in many regions of the world have led to a comprehensive reuse of treated wastewater that, ultimately, may cause a long-term concentration buildup of many toxic persistent organic pollutants (POPs) in the closed cycle of water supply and wastewater treatment and reuse. The endocrinic/mutagenic potencies of the EDCs-branched chain alkylphenol ethoxylates (APEOs), polycyclic aromatic hydrocarbons (PAHs), and their metabolites are well-documented. From approximately 5.5 x 108 m3/y of sewage produced in Israel, approximately 70% are reused, following a conventional, or advanced, activated sludge or sand aquifer treatment (SAT). A major related question is: Does this practice conform to sustainability? Our studies reveal that (a) the concentrations of APEOs and PAHs in Israel rivers and sediments do pose a potential health risk problem; and (b) the synergistic ecotoxicologic impact of environmentally relevant mixtures of these POPs, in WWTP effluents, constitutes an inconsistency, healthwise, with sustainability practice. FAU - Zoller, Uri AU - Zoller U AD - Faculty of Natural Sciences, Haifa University--Oranim, Kiryat Tivon 36006, Israel. uriz@research.haifa.ac.il FAU - Hushan, Marwan AU - Hushan M LA - eng PT - Journal Article PL - Germany TA - Rev Environ Health JT - Reviews on environmental health JID - 0425754 RN - 0 (Endocrine Disruptors) RN - 0 (Ethyl Ethers) RN - 0 (Polycyclic Aromatic Hydrocarbons) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Endocrine Disruptors/*analysis MH - Ethyl Ethers/*analysis MH - Fresh Water/*chemistry MH - Humans MH - Israel MH - Polycyclic Aromatic Hydrocarbons/*analysis MH - Waste Disposal, Fluid/methods MH - Water Pollutants, Chemical/*analysis MH - Water Pollution, Chemical/*analysis EDAT- 2011/01/28 06:00 MHDA- 2011/02/22 06:00 CRDT- 2011/01/28 06:00 PHST- 2011/01/28 06:00 [entrez] PHST- 2011/01/28 06:00 [pubmed] PHST- 2011/02/22 06:00 [medline] AID - 10.1515/reveh.2010.25.4.351 [doi] PST - ppublish SO - Rev Environ Health. 2010 Oct-Dec;25(4):351-7. doi: 10.1515/reveh.2010.25.4.351.