PMID- 21270998
OWN - NLM
STAT- MEDLINE
DCOM- 20110620
LR  - 20161125
IS  - 1464-0333 (Electronic)
IS  - 1464-0325 (Linking)
VI  - 13
IP  - 3
DP  - 2011 Mar
TI  - PBDEs and PCBs in the liver of the St Lawrence Estuary beluga (Delphinapterus 
      leucas): a comparison of levels and temporal trends with the blubber.
PG  - 649-56
LID - 10.1039/c0em00310g [doi]
AB  - Due to their lipophilic properties, persistent organic pollutants (POPs) are 
      commonly assessed using the blubber of marine mammals. However, these chemicals 
      are also accumulating in other tissues including the liver. Some pollutants, 
      namely perfluorinated alkyl acids, are found predominately in the liver and blood 
      of marine mammals, and thus monitored in those tissues. This raises the question 
      whether any tissue would represent an identical trend of POPs in the SLE beluga. 
      The current study reports the first temporal trends of PBDEs and PCBs in the 
      liver of 65 SLE belugas. Neither  summation operator(7)PBDEs nor major individual PBDE-homolog group 
      concentrations showed significant trends between 1993 and 2007. Also,  summation operator(3)(2)PCBs did 
      not change over years, although, tetra-, penta- and hepta-PCB decreased by 7.1, 
      6.8 and 8.5%, respectively, in males, whereas tetra-, penta- and octa-PCBs 
      declined by 11, 12 and 12.9%, respectively, in females. In order to compare the 
      distribution of POPs between liver and blubber, a lipid normalised concentration 
      ratio R (blubber/liver) for PBDEs and PCBs was calculated for each individual 
      beluga. For all PBDE and several PCB homolog groups, mean R values were not 
      statistically different from unity indicating that the partitioning of these POPs 
      is governed by the tissue lipid-content. Temporal trends of R ratios of PBDEs and 
      PCBs were also examined. There were generally no significant temporal trends 
      except for PBDEs in males where R increased in average by 12.7 +/- 2.9% yearly. The 
      stratification of the blubber into a metabolically active (inner) and less active 
      layers (outer blubber) may result in a slower response time of the blubber (full 
      depth) than the liver to the recent change of contamination in the environment 
      and explain the time trend differences between both tissues. This study suggests 
      that the liver is more representative of recent exposure to lipophilic 
      contaminants.
FAU - Raach, Meriem
AU  - Raach M
AD  - Institut des Sciences de la Mer de Rimouski, Universite du Quebec a Rimouski, 
      Rimouski, Quebec, Canada. meriem.raach@uqar.qc.ca
FAU - Lebeuf, Michel
AU  - Lebeuf M
FAU - Pelletier, Emilien
AU  - Pelletier E
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20110127
PL  - England
TA  - J Environ Monit
JT  - Journal of environmental monitoring : JEM
JID - 100968688
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 7REL09ZX35 (pentabromodiphenyl ether)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adipose Tissue/chemistry
MH  - Animals
MH  - Atlantic Ocean
MH  - *Beluga Whale
MH  - Environmental Pollutants/*analysis
MH  - Female
MH  - Halogenated Diphenyl Ethers/*analysis
MH  - Liver/*chemistry
MH  - Male
MH  - Polychlorinated Biphenyls/*analysis
MH  - Quebec
MH  - Time Factors
EDAT- 2011/01/29 06:00
MHDA- 2011/06/21 06:00
CRDT- 2011/01/29 06:00
PHST- 2011/01/29 06:00 [entrez]
PHST- 2011/01/29 06:00 [pubmed]
PHST- 2011/06/21 06:00 [medline]
AID - 10.1039/c0em00310g [doi]
PST - ppublish
SO  - J Environ Monit. 2011 Mar;13(3):649-56. doi: 10.1039/c0em00310g. Epub 2011 Jan 
      27.