PMID- 21272407
OWN - NLM
STAT- MEDLINE
DCOM- 20110712
LR  - 20220318
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 105
IP  - 10
DP  - 2011 May
TI  - Growth, body composition and hormonal status of growing pigs exhibiting a normal 
      or small weight at birth and exposed to a neonatal diet enriched in proteins.
PG  - 1471-9
LID - 10.1017/S0007114510005386 [doi]
AB  - Small birth weight and excess of early protein intake are suspected to enhance 
      later obesity risk. The present study was undertaken to determine the impact of 
      neonatal diets differing in protein content on growth, body composition and 
      hormonal status of 70-d-old pigs born with normal weight (NW) or small weight 
      (SW). At 7 d of age, male and female suckled piglets were assigned to the NW 
      (approximately 1.4 kg at birth) or SW (approximately 0.99 kg at birth) groups. 
      They were fed milk replacers formulated to provide an adequate protein (AP) or a 
      high protein (HP) supply for 3 weeks. From weaning to 70 d of age, all animals 
      received ad libitum the same standard diet. Growth rates were higher (P < 0.05) 
      in HP piglets than in AP piglets during formula feeding and remained higher (P < 
      0.05) only in HP male pigs thereafter. No difference in feed consumption was 
      detected between groups during the periods examined. Carcass lipid content and 
      the relative weight of perirenal adipose tissue did not differ between the AP and 
      HP pigs. Whereas plasma leptin concentration was higher (P < 0.05) in HP pigs 
      than in AP pigs with a marked difference in SW pigs, plasma insulin-like growth 
      factor (IGF)-I concentration and expression of IGF system genes were not affected 
      by the diets. In summary, a HP intake during the suckling period induced an 
      increase in growth rate that persisted only in male pigs during the post-weaning 
      period. This response was not associated with any difference in adiposity 
      parameters in this period.
FAU - Morise, Anne
AU  - Morise A
AD  - INRA, UMR Systemes d'Elevage Nutrition Animale et Humaine, Saint-Gilles, France.
FAU - Seve, Bernard
AU  - Seve B
FAU - Mace, Katherine
AU  - Mace K
FAU - Magliola, Corinne
AU  - Magliola C
FAU - Le Huerou-Luron, Isabelle
AU  - Le Huerou-Luron I
FAU - Louveau, Isabelle
AU  - Louveau I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110128
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Dietary Proteins)
RN  - 0 (Hormones)
SB  - IM
MH  - Animals
MH  - *Animals, Newborn
MH  - *Birth Weight
MH  - *Body Composition
MH  - Dietary Proteins/*administration & dosage
MH  - Hormones/*metabolism
MH  - Swine/*growth & development
EDAT- 2011/01/29 06:00
MHDA- 2011/07/13 06:00
CRDT- 2011/01/29 06:00
PHST- 2011/01/29 06:00 [entrez]
PHST- 2011/01/29 06:00 [pubmed]
PHST- 2011/07/13 06:00 [medline]
AID - S0007114510005386 [pii]
AID - 10.1017/S0007114510005386 [doi]
PST - ppublish
SO  - Br J Nutr. 2011 May;105(10):1471-9. doi: 10.1017/S0007114510005386. Epub 2011 Jan 
      28.