PMID- 21277223
OWN - NLM
STAT- MEDLINE
DCOM- 20110621
LR  - 20211020
IS  - 1096-3618 (Electronic)
IS  - 1044-5323 (Print)
IS  - 1044-5323 (Linking)
VI  - 23
IP  - 1
DP  - 2011 Feb
TI  - Targeting human dendritic cell subsets for improved vaccines.
PG  - 21-7
LID - 10.1016/j.smim.2011.01.004 [doi]
AB  - Dendritic cells (DCs) were discovered in 1973 by Ralph Steinman as a previously 
      undefined cell type in the mouse spleen and are now recognized as a group of 
      related cell populations that induce and regulate adaptive immune responses. 
      Studies of the past decade show that, both in mice and humans, DCs are composed 
      of subsets that differ in their localization, phenotype, and functions. These 
      progresses in our understanding of DC biology provide a new framework for 
      improving human health. In this review, we discuss human DC subsets in the 
      context of their medical applications, with a particular focus on DC targeting.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Ueno, Hideki
AU  - Ueno H
AD  - Baylor Institute for Immunology Research, Baylor Research Institute, 3434 Live 
      Oak, Dallas, TX 75204, USA. hidekiu@baylorhealth.edu
FAU - Klechevsky, Eynav
AU  - Klechevsky E
FAU - Schmitt, Nathalie
AU  - Schmitt N
FAU - Ni, Ling
AU  - Ni L
FAU - Flamar, Anne-Laure
AU  - Flamar AL
FAU - Zurawski, Sandra
AU  - Zurawski S
FAU - Zurawski, Gerard
AU  - Zurawski G
FAU - Palucka, Karolina
AU  - Palucka K
FAU - Banchereau, Jacques
AU  - Banchereau J
FAU - Oh, Sangkon
AU  - Oh S
LA  - eng
GR  - U19 AI057234-06S1/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-07/CA/NCI NIH HHS/United States
GR  - R01 CA078846-08/CA/NCI NIH HHS/United States
GR  - R01 CA078846-01A1/CA/NCI NIH HHS/United States
GR  - U19 AI057234-05S1/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-02/CA/NCI NIH HHS/United States
GR  - U19 AI057234-07/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-06S3/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-04/AI/NIAID NIH HHS/United States
GR  - R01 CA140602/CA/NCI NIH HHS/United States
GR  - R01 CA089440-04/CA/NCI NIH HHS/United States
GR  - R01 CA089440-02/CA/NCI NIH HHS/United States
GR  - U19 AI057234-02/AI/NIAID NIH HHS/United States
GR  - R01 CA089440-01A1/CA/NCI NIH HHS/United States
GR  - R01 CA078846-04/CA/NCI NIH HHS/United States
GR  - U19 AI057234-01/AI/NIAID NIH HHS/United States
GR  - U19 AI089987-02/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-07S1/CA/NCI NIH HHS/United States
GR  - U19 AI057234-07S1/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-05A2/CA/NCI NIH HHS/United States
GR  - R01 CA078846-05/CA/NCI NIH HHS/United States
GR  - U19 AI057234-05/AI/NIAID NIH HHS/United States
GR  - U19 AI089987-01/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-07S2/CA/NCI NIH HHS/United States
GR  - P01 CA084512/CA/NCI NIH HHS/United States
GR  - U19 AI057234-08/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-10/CA/NCI NIH HHS/United States
GR  - P01 CA084512-06/CA/NCI NIH HHS/United States
GR  - R01 CA078846-06/CA/NCI NIH HHS/United States
GR  - U19 AI057234-06/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-09/CA/NCI NIH HHS/United States
GR  - U19 AI057234/AI/NIAID NIH HHS/United States
GR  - R01 CA089440/CA/NCI NIH HHS/United States
GR  - U19 AI057234-06S2/AI/NIAID NIH HHS/United States
GR  - U19 AIO57234/PHS HHS/United States
GR  - R01 CA089440-03/CA/NCI NIH HHS/United States
GR  - U19 AI057234-03/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-03/CA/NCI NIH HHS/United States
GR  - R01 CA078846/CA/NCI NIH HHS/United States
GR  - P01 CA084514/CA/NCI NIH HHS/United States
GR  - U19 AI089987/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-07/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20110128
PL  - England
TA  - Semin Immunol
JT  - Seminars in immunology
JID - 9009458
RN  - 0 (Vaccines)
SB  - IM
MH  - Animals
MH  - Dendritic Cells/classification/*immunology
MH  - Humans
MH  - Vaccines/*immunology
PMC - PMC3071344
MID - NIHMS269531
EDAT- 2011/02/01 06:00
MHDA- 2011/06/22 06:00
PMCR- 2012/02/01
CRDT- 2011/02/01 06:00
PHST- 2010/11/10 00:00 [received]
PHST- 2011/01/05 00:00 [accepted]
PHST- 2011/02/01 06:00 [entrez]
PHST- 2011/02/01 06:00 [pubmed]
PHST- 2011/06/22 06:00 [medline]
PHST- 2012/02/01 00:00 [pmc-release]
AID - S1044-5323(11)00005-4 [pii]
AID - 10.1016/j.smim.2011.01.004 [doi]
PST - ppublish
SO  - Semin Immunol. 2011 Feb;23(1):21-7. doi: 10.1016/j.smim.2011.01.004. Epub 2011 
      Jan 28.