PMID- 21284993
OWN - NLM
STAT- MEDLINE
DCOM- 20110421
LR  - 20161125
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 83
IP  - 2
DP  - 2011 Mar
TI  - Carry-over of dietary organochlorine pesticides, PCDD/Fs, PCBs, and brominated 
      flame retardants to Atlantic salmon (Salmo salar L.) fillets.
PG  - 95-103
LID - 10.1016/j.chemosphere.2011.01.017 [doi]
AB  - Information on carry-over of contaminants from feed to animal food products is 
      essential for appropriate human risk assessment of feed contaminants. The 
      carry-over of potentially hazardous persistent organic pollutants (POPs) from 
      feed to fillet was assessed in consumption sized Atlantic salmon (Salmo salar). 
      Relative carry-over (defined as the fraction of a certain dietary POP retained in 
      the fillet) was assessed in a controlled feeding trial, which provided fillet 
      retention of dietary organochlorine pesticides (OCPs), dioxins (PCDD/Fs), 
      polychlorinated biphenyls (PCBs), and brominated flame retardants (BFRs). Highest 
      retention was found for OCPs, BFRs and PCBs (31-58%), and the lowest retentions 
      were observed for PCDD/Fs congeners (10-34%). National monitoring data on 
      commercial fish feed and farmed Atlantic salmon on the Norwegian market were used 
      to provide commercially relevant feed-to-fillet transfer factors (calculated as 
      fillet POP level divided by feed POP level), which ranged from 0.4 to 0.5, which 
      is a factor 5-10 times higher than reported for terrestrial meat products. For 
      the OCP with one of the highest relative carry-over, toxaphene, uptake and 
      elimination kinetics were established. Model simulations that are based on the 
      uptake and elimination kinetics gave predicted levels that were in agreement with 
      the measured values. Application of the model to the current EU upper limit for 
      toxaphene in feed (50 mug kg(-1)) gave maximum fillet levels of 22 mug kg(-1), 
      which exceeds the estimated permissible level (21 mug kg(-1)) for toxaphene in 
      fish food samples in Norway.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Berntssen, Marc H G
AU  - Berntssen MH
AD  - National Institute of Nutrition and Seafood Research, Bergen, Norway. 
      marc.berntssen@nifes.no
FAU - Maage, A
AU  - Maage A
FAU - Julshamn, K
AU  - Julshamn K
FAU - Oeye, B E
AU  - Oeye BE
FAU - Lundebye, A-K
AU  - Lundebye AK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110201
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Benzofurans)
RN  - 0 (Bromine Compounds)
RN  - 0 (Dibenzofurans, Polychlorinated)
RN  - 0 (Flame Retardants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Water Pollutants, Chemical)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animal Feed/analysis
MH  - Animals
MH  - Benzofurans/analysis/metabolism
MH  - Bromine Compounds/analysis/metabolism
MH  - Dibenzofurans, Polychlorinated
MH  - Diet/statistics & numerical data
MH  - Environmental Exposure/analysis/statistics & numerical data
MH  - Flame Retardants/*analysis/metabolism
MH  - Humans
MH  - Hydrocarbons, Chlorinated/analysis/metabolism
MH  - Pesticides/*analysis/metabolism
MH  - Polychlorinated Biphenyls/*analysis/metabolism
MH  - Polychlorinated Dibenzodioxins/*analogs & derivatives/analysis/metabolism
MH  - Salmo salar/*metabolism
MH  - Seafood/analysis
MH  - Water Pollutants, Chemical/*analysis/metabolism
EDAT- 2011/02/03 06:00
MHDA- 2011/04/22 06:00
CRDT- 2011/02/03 06:00
PHST- 2010/10/18 00:00 [received]
PHST- 2010/12/22 00:00 [revised]
PHST- 2011/01/05 00:00 [accepted]
PHST- 2011/02/03 06:00 [entrez]
PHST- 2011/02/03 06:00 [pubmed]
PHST- 2011/04/22 06:00 [medline]
AID - S0045-6535(11)00019-1 [pii]
AID - 10.1016/j.chemosphere.2011.01.017 [doi]
PST - ppublish
SO  - Chemosphere. 2011 Mar;83(2):95-103. doi: 10.1016/j.chemosphere.2011.01.017. Epub 
      2011 Feb 1.