PMID- 21289022
OWN - NLM
STAT- MEDLINE
DCOM- 20110808
LR  - 20110322
IS  - 1472-3263 (Electronic)
IS  - 1368-4973 (Linking)
VI  - 87
IP  - 3
DP  - 2011 Apr
TI  - Health-related quality of life in Indian patients with three viral sexually 
      transmitted infections: herpes simplex virus-2, genital human papilloma virus and 
      HIV.
PG  - 216-20
LID - 10.1136/sti.2010.043356 [doi]
AB  - BACKGROUND: Health-related quality of life (HRQOL) has not been studied in Indian 
      patients with viral sexually transmitted infections (STIs): herpes simplex 
      virus-2 (HSV-2) and genital human papilloma virus (HPV) infections. Furthermore, 
      there is no reported study that compares HRQOL among these two viral STIs and 
      HIV. METHODS: All consenting adults with any of the three viral infections 
      attending a sexually transmitted disease clinic and 35 healthy controls were 
      enrolled. HRQOL was evaluated using the WHOQOL-BREF instrument, which evaluates 
      QOL under physical, psychological, social and environmental domains. Data 
      concerning demographic and socioeconomic status were collected. RESULTS: There 
      were 65 (27.3%), 60 (25.2%) and 53 (22.3%) patients with HIV, HSV-2 and HPV, 
      respectively, and 25 (10.5%) patients with mixed infections. The WHOQOL-BREF 
      scores of patients in different STI groups were significantly lower than those of 
      controls. The total HRQOL scores (mean+/-SD) were 280.1+/-83.56 (among controls), 
      196.9+/-72.41 (genital HPV), 141.0+/-50.50 (HSV-2), 101.0+/-75.25 (HIV) and 
      103.4+/-47.23(mixed infection groups). Mean HRQOL scores were lowest in the 
      physical and psychological domains. HRQOL scores were least in HIV and mixed 
      infections groups, while patients with genital HPV infection had significantly 
      better HRQOL scores compared to other patient groups. Higher education and 
      socioeconomic status had a positive influence on HRQOL. CONCLUSION: Viral STIs 
      were associated with a significant reduction in HRQOL scores. Among patient 
      groups, the greatest impact on HRQOL was seen in those with HIV and mixed 
      infections and the least impact seen in those with genital HPV infection. 
      Comprehensive care including counselling services need to be implemented in STI 
      clinics.
FAU - Raj, Rama
AU  - Raj R
AD  - Department of Dermatology and Venereology, All India Institute of Medical 
      Sciences, New Delhi-110029, India.
FAU - Sreenivas, Vishnubhatla
AU  - Sreenivas V
FAU - Mehta, Manju
AU  - Mehta M
FAU - Gupta, Somesh
AU  - Gupta S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20110202
PL  - England
TA  - Sex Transm Infect
JT  - Sexually transmitted infections
JID - 9805554
SB  - IM
MH  - Adult
MH  - Aged
MH  - Condylomata Acuminata/epidemiology/*psychology
MH  - Female
MH  - HIV Infections/epidemiology/*psychology
MH  - Health Status
MH  - Herpes Genitalis/epidemiology/*psychology
MH  - Herpesvirus 2, Human
MH  - Humans
MH  - India/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - Rural Health
MH  - Socioeconomic Factors
MH  - Urban Health
MH  - Young Adult
EDAT- 2011/02/04 06:00
MHDA- 2011/08/09 06:00
CRDT- 2011/02/04 06:00
PHST- 2011/02/04 06:00 [entrez]
PHST- 2011/02/04 06:00 [pubmed]
PHST- 2011/08/09 06:00 [medline]
AID - sti.2010.043356 [pii]
AID - 10.1136/sti.2010.043356 [doi]
PST - ppublish
SO  - Sex Transm Infect. 2011 Apr;87(3):216-20. doi: 10.1136/sti.2010.043356. Epub 2011 
      Feb 2.