PMID- 21298310 OWN - NLM STAT- MEDLINE DCOM- 20120719 LR - 20211020 IS - 1590-3478 (Electronic) IS - 1590-1874 (Linking) VI - 33 IP - 1 DP - 2012 Feb TI - Two cases of dementias with motor neuron disease evaluated by Pittsburgh compound B-positron emission tomography. PG - 87-92 LID - 10.1007/s10072-011-0479-6 [doi] AB - We described the cases of two patients with dementia associated with motor neuron disease, the former with frontotemporal dementia (FTD) and the latter with Alzheimer's disease (AD), studied by the Pittsburgh compound B-positron emission tomography (PIB-PET). In the FTD patient, the PIB-PET revealed no amyloid accumulation in the cortex, whilst in the AD patient showed amyloid accumulation mainly in the frontal, parietal and lateral temporal lobes, besides the posterior cingulate gyrus and the precuneus. Thus, PIB-PET might facilitate the discrimination of different proteinopathies that cause neurodegenerative diseases, as dementia associated with ALS. FAU - Yamakawa, Yoshihiro AU - Yamakawa Y AD - Department of Geriatric Medicine and Neurology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8586, Japan. FAU - Shimada, Hiroyuki AU - Shimada H FAU - Ataka, Suzuka AU - Ataka S FAU - Tamura, Akiko AU - Tamura A FAU - Masaki, Hideki AU - Masaki H FAU - Naka, Hiroshi AU - Naka H FAU - Tsutada, Tsuyoshi AU - Tsutada T FAU - Nakanishi, Aki AU - Nakanishi A FAU - Shiomi, Susumu AU - Shiomi S FAU - Watanabe, Yasuyoshi AU - Watanabe Y FAU - Miki, Takami AU - Miki T LA - eng PT - Case Reports PT - Journal Article DEP - 20110205 PL - Italy TA - Neurol Sci JT - Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology JID - 100959175 RN - 0 (2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole) RN - 0 (Aniline Compounds) RN - 0 (Thiazoles) SB - IM MH - Aged MH - Alzheimer Disease/*diagnostic imaging MH - *Aniline Compounds MH - Brain/*diagnostic imaging MH - Diagnosis, Differential MH - Female MH - Frontotemporal Dementia/*diagnostic imaging MH - Humans MH - Male MH - Middle Aged MH - Motor Neuron Disease/diagnostic imaging MH - Positron-Emission Tomography/methods MH - *Thiazoles EDAT- 2011/02/08 06:00 MHDA- 2012/07/20 06:00 CRDT- 2011/02/08 06:00 PHST- 2010/08/01 00:00 [received] PHST- 2011/01/11 00:00 [accepted] PHST- 2011/02/08 06:00 [entrez] PHST- 2011/02/08 06:00 [pubmed] PHST- 2012/07/20 06:00 [medline] AID - 10.1007/s10072-011-0479-6 [doi] PST - ppublish SO - Neurol Sci. 2012 Feb;33(1):87-92. doi: 10.1007/s10072-011-0479-6. Epub 2011 Feb 5.