PMID- 21300304
OWN - NLM
STAT- MEDLINE
DCOM- 20110602
LR  - 20191210
IS  - 1532-8414 (Electronic)
IS  - 1071-9164 (Linking)
VI  - 17
IP  - 2
DP  - 2011 Feb
TI  - Evaluation of the Health Utilities Index Mark-3 in heart failure.
PG  - 143-50
LID - 10.1016/j.cardfail.2010.08.014 [doi]
AB  - BACKGROUND: The purpose of this study was to evaluate the reliability, validity, 
      and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in 
      heart failure (HF) for use in cost-effectiveness studies. METHODS AND RESULTS: 
      Two hundred eleven patients with HF recruited from outpatient clinics were 
      enrolled; 165 completed the 26-week study. Patients completed 4 health-related 
      quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the 
      HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living 
      with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure 
      Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality 
      of life overall; the attributes most impaired were pain, ambulation, cognition, 
      and emotion. Internal consistency reliability (Cronbach's alpha = 0.51) was low 
      and test-retest reliability (intraclass correlation coefficient = 0.68) was 
      adequate. The HUI-3 total score was significantly associated with the SF-12, 
      LHFQ, and CHQ total scores. It discriminated among patients with varying New York 
      Heart Association class (P < .001) and varying perceived health (P < .001). The 
      HUI-3 was less responsive to perceived change in health condition than the LHFQ 
      or the CHQ. CONCLUSIONS: The HUI-3 demonstrated satisfactory reliability and 
      validity in this sample supporting its use in cost-effectiveness studies.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Pressler, Susan J
AU  - Pressler SJ
AD  - The University of Michigan School of Nursing, 400 N. Ingalls, Ann Arbor, MI 
      48109, USA. spressle@umich.edu
FAU - Eckert, George J
AU  - Eckert GJ
FAU - Morrison, Gwendolyn C
AU  - Morrison GC
FAU - Murray, Michael D
AU  - Murray MD
FAU - Oldridge, Neil B
AU  - Oldridge NB
LA  - eng
GR  - R03 HS09822-01/HS/AHRQ HHS/United States
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20101028
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cost-Benefit Analysis
MH  - Female
MH  - *Health Status Indicators
MH  - Heart Failure/*diagnosis/pathology/psychology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psychometrics
MH  - Quality of Life/*psychology
MH  - Reproducibility of Results
MH  - Statistics, Nonparametric
MH  - Surveys and Questionnaires
MH  - Young Adult
EDAT- 2011/02/09 06:00
MHDA- 2011/06/03 06:00
CRDT- 2011/02/09 06:00
PHST- 2010/06/24 00:00 [received]
PHST- 2010/08/20 00:00 [revised]
PHST- 2010/08/30 00:00 [accepted]
PHST- 2011/02/09 06:00 [entrez]
PHST- 2011/02/09 06:00 [pubmed]
PHST- 2011/06/03 06:00 [medline]
AID - S1071-9164(10)01094-8 [pii]
AID - 10.1016/j.cardfail.2010.08.014 [doi]
PST - ppublish
SO  - J Card Fail. 2011 Feb;17(2):143-50. doi: 10.1016/j.cardfail.2010.08.014. Epub 
      2010 Oct 28.