PMID- 21306686 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20110210 IS - 1009-3419 (Print) IS - 1009-3419 (Linking) VI - 6 IP - 5 DP - 2003 Oct 20 TI - [A clinical study on paclitaxel plus cisplatin combined therapy in the treatment of non-small cell lung cancer]. PG - 386-7 LID - 10.3779/j.issn.1009-3419.2003.05.16 [doi] AB - BACKGROUND: To evaluate the results of combined chemotherapy with paclitaxel (PTX, taxol) plus cisplatin (DDP) in the treatment of advanced non small cell lung cancer (NSCLC). METHODS: From January 1997 to December 2002, forty-seven patients with advanced non-small cell lung cancer received PTX 135-180 mg/m(2) by intravenous infusion, on day 1, and DDP 40 mg/time by intravenous infusion,on days 1-3. The treatment was repeated every 3 weeks, up to 2 or 3 cycles. RESULTS: Forty-six patients were evaluable for efficacy. One patient got complete response (2.2%), and 16 got partial response (34.8%), with an overall response rate of 37.0%. The main toxicities were myelosuppression, nausea and vomiting, and other side effects were mild. CONCLUSIONS: A high response rate can be obtained in advanced NSCLC by PTX plus DDP. PTX is a promising antitumor agent with tolerable toxicity. FAU - Chen, Zhen AU - Chen Z AD - Department of Chemotherapy, Shandong Provincial Tumor Hospital, Jinan, Shandong 250117, P.R.China. FAU - Wang, Zhehai AU - Wang Z FAU - Li, Changzheng AU - Li C LA - chi PT - English Abstract PT - Journal Article PL - China TA - Zhongguo Fei Ai Za Zhi JT - Zhongguo fei ai za zhi = Chinese journal of lung cancer JID - 101126433 EDAT- 2003/10/20 00:00 MHDA- 2003/10/20 00:01 CRDT- 2011/02/11 06:00 PHST- 2011/02/11 06:00 [entrez] PHST- 2003/10/20 00:00 [pubmed] PHST- 2003/10/20 00:01 [medline] AID - 10.3779/j.issn.1009-3419.2003.05.16 [doi] PST - ppublish SO - Zhongguo Fei Ai Za Zhi. 2003 Oct 20;6(5):386-7. doi: 10.3779/j.issn.1009-3419.2003.05.16.