PMID- 21309510
OWN - NLM
STAT- MEDLINE
DCOM- 20110630
LR  - 20151119
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 59
IP  - 5
DP  - 2011 Mar 9
TI  - Metabolism of a new herbicide, [(14)c]pyribenzoxim, in rice.
PG  - 1918-23
LID - 10.1021/jf1039469 [doi]
AB  - The in vivo metabolism of a new herbicide pyribenzoxim (benzophenone 
      Omicron-[2,6-bis(4,6-dimethoxypyrimidin-2-yloxy)benzoyl]oxime) in rice was carried out 
      using container trials. Two radiolabeled forms of [carbonyl-(14)C]pyribenzoxim 
      (P1) and [ring-(14)C(U)]pyribenzoxim (P2) were treated separately as formulations 
      for foliar treatment by single applications of 50 g of active ingredient (ai)/ha 
      at the 4-6 leaves stage. At 0, 7, 30, and 60 days after treatment (DAT), samples 
      of panicle, foliage/rest of plant, and roots were taken for analysis. Upon 
      harvest (120 DAT), rice plants were separated into grain, husk, straw, and root 
      parts. Total radioactive residues (TRRs) at each sampling date were determined to 
      show that the final radioactive residues at harvest were low in grain, husk, 
      straw, and roots, accounting for <17 ppb. The concentration of final residues in 
      the rice plant decreased rapidly, and less than 0.1% of initial TRRs remained at 
      harvest. At 7 DAT, metabolite 1 [M1, 
      2,6-bis(4,6-dimethoxypyrimidin-2-yloxy)benzoic acid] and two unknown compounds 
      (other-1 and other-2) were detected in foliage extract, accounting for 3.5% TRRs 
      (21.0 ppb), 3.1% TRRs (19.0 ppb), and 9.0% TRRs (54.3 ppb), respectively, while 
      26.1% of M1 was observed in solvent wash. Any other metabolites were not detected 
      in the plant, including expected metabolite M3 (benzophenone oxime). On the basis 
      of the results obtained, a metabolic pathway of pyribenzoxim in a rice plant was 
      proposed.
FAU - Chang, Hee-Ra
AU  - Chang HR
AD  - Environmental Toxicology Division, Toxicological Research Center, Hoseo 
      University , 165 Sechul, Baebang, Asan, Chungnam 336-795, Korea.
FAU - Keum, Young Soo
AU  - Keum YS
FAU - Koo, Suk-Jin
AU  - Koo SJ
FAU - Moon, Joon-Kwan
AU  - Moon JK
FAU - Kim, Kyun
AU  - Kim K
FAU - Kim, Jeong-Han
AU  - Kim JH
LA  - eng
PT  - Journal Article
DEP - 20110210
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Benzophenones)
RN  - 0 (Carbon Radioisotopes)
RN  - 0 (Herbicides)
RN  - 0 (benzophenone O-(2,6-bis(4,6-dimethoxypyrimidin-2-yloxy)benzoyl)oxime)
SB  - IM
MH  - Benzophenones/administration & dosage/analysis/*metabolism
MH  - Carbon Radioisotopes
MH  - Herbicides/*metabolism
MH  - Oryza/chemistry/growth & development/*metabolism
MH  - Plant Leaves/chemistry
MH  - Plant Roots/chemistry
EDAT- 2011/02/12 06:00
MHDA- 2011/07/01 06:00
CRDT- 2011/02/12 06:00
PHST- 2011/02/12 06:00 [entrez]
PHST- 2011/02/12 06:00 [pubmed]
PHST- 2011/07/01 06:00 [medline]
AID - 10.1021/jf1039469 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2011 Mar 9;59(5):1918-23. doi: 10.1021/jf1039469. Epub 2011 
      Feb 10.