PMID- 21318164
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 2042-0056 (Electronic)
IS  - 2090-8105 (Print)
VI  - 2010
DP  - 2011 Jan 17
TI  - Ankle blood pressure and pulse pressure as predictors of cerebrovascular 
      morbidity and mortality in a prospective follow-up study.
PG  - 729391
LID - 10.4061/2010/729391 [doi]
LID - 729391
AB  - Background and Objective. We examined the association of elevated ankle blood 
      pressure (ABP), together with exercise blood pressure, with incident 
      cerebrovascular (CV) morbidity and mortality in a prospective follow-up study of 
      3,808 patients. The results were compared with pulse pressure, another indicator 
      of arterial stiffness. Methods. Patients with normal ankle and exercise brachial 
      blood pressures were taken as the reference group. Pulse pressure was considered 
      as quartiles with the lowest quartile as the reference category. Results. A total 
      of 170 subjects had a CV event during the follow-up. Multivariate adjusted hazard 
      ratio of a CV event was 2.24 (95% CI 1.43-3.52, P < .0001) in patients with 
      abnormal ABP. The pulse pressure was significant only in the model adjusted for 
      age and sex. Conclusion. The risk of a future CV event was elevated already in 
      those patients among whom elevated ABP was the only abnormal finding. As a risk 
      marker, ABP is superior to the pulse pressure.
FAU - Hietanen, Heikki J
AU  - Hietanen HJ
AD  - Department of Clinical Physiology, Helsinki Deaconess Institute, Alppikatu 2, 
      00530 Helsinki, Finland.
FAU - Paakkonen, Rauni
AU  - Paakkonen R
FAU - Salomaa, Veikko
AU  - Salomaa V
LA  - eng
PT  - Journal Article
DEP - 20110117
PL  - United States
TA  - Stroke Res Treat
JT  - Stroke research and treatment
JID - 101529024
PMC - PMC3026983
EDAT- 2011/02/15 06:00
MHDA- 2011/02/15 06:01
PMCR- 2011/01/17
CRDT- 2011/02/15 06:00
PHST- 2010/08/23 00:00 [received]
PHST- 2010/11/24 00:00 [revised]
PHST- 2010/12/23 00:00 [accepted]
PHST- 2011/02/15 06:00 [entrez]
PHST- 2011/02/15 06:00 [pubmed]
PHST- 2011/02/15 06:01 [medline]
PHST- 2011/01/17 00:00 [pmc-release]
AID - 10.4061/2010/729391 [doi]
PST - epublish
SO  - Stroke Res Treat. 2011 Jan 17;2010:729391. doi: 10.4061/2010/729391.