PMID- 21321445
OWN - NLM
STAT- MEDLINE
DCOM- 20110729
LR  - 20190827
IS  - 1348-2246 (Electronic)
IS  - 0910-6340 (Linking)
VI  - 27
IP  - 2
DP  - 2011
TI  - Determination of triclosan in aqueous samples using solid-phase extraction 
      followed by on-line derivatization gas chromatography-mass spectrometry.
PG  - 197-202
AB  - An efficient and eco-friendly injection-port tert-butyldimethylsilylated (TBDMS) 
      derivatization and gas chromatography-mass spectrometry (GC/MS) were developed to 
      determine an antibacterial agent, triclosan (TCS), and its metabolite: 
      methyltriclosan (MTCS), in wastewater and surface water samples. The effects of 
      several parameters related to the TBDMS-derivatization process (i.e., 
      injection-port temperature, residence time and volume of silylating agent) were 
      investigated. This on-line derivatization-coupled large-volume (10 microL) sample 
      introduction provides sensitive, fast and reproducible results for TCS residue 
      analyses. Each water sample was extracted by reversed-phase C18 solid-phase 
      extraction (SPE) cartridge, and then the recovery efficiency was evaluated using 
      various eluting solutions. Limits of quantitation (LOQs) for MTCS and TCS were 
      3.0 and 1.0 ng/L in 100 mL of water samples, respectively. Intra- and inter-batch 
      precision with their accuracy were also investigated. The precision for these 
      analytes, as indicated by relative standard deviations (RSDs), proved to be less 
      than 7 and 11%, respectively, for intra- and inter-batch. Accuracy, expressed as 
      the mean recovery, was between 80 and 95%. The method was then applied to 
      environmental water samples, showing the occurrence of TCS in both surface water 
      and municipal wastewater treatment plant (MWTP) influent/effluent samples.
FAU - Cheng, Chiao-Yin
AU  - Cheng CY
AD  - Department of Chemistry, National Central University, Chung-Li 320, Taiwan.
FAU - Wang, Yu-Chen
AU  - Wang YC
FAU - Ding, Wang-Hsien
AU  - Ding WH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Anal Sci
JT  - Analytical sciences : the international journal of the Japan Society for 
      Analytical Chemistry
JID - 8511078
RN  - 059QF0KO0R (Water)
RN  - 4NM5039Y5X (Triclosan)
SB  - IM
MH  - Drug Residues/*analysis/chemistry/*isolation & purification/metabolism
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Injections
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Triclosan/*analysis/chemistry/*isolation & purification/metabolism
MH  - Water/*chemistry
EDAT- 2011/02/16 06:00
MHDA- 2011/07/30 06:00
CRDT- 2011/02/16 06:00
PHST- 2011/02/16 06:00 [entrez]
PHST- 2011/02/16 06:00 [pubmed]
PHST- 2011/07/30 06:00 [medline]
AID - JST.JSTAGE/analsci/27.197 [pii]
AID - 10.2116/analsci.27.197 [doi]
PST - ppublish
SO  - Anal Sci. 2011;27(2):197-202. doi: 10.2116/analsci.27.197.