PMID- 21324274
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110217
IS  - 1009-3419 (Print)
IS  - 1009-3419 (Linking)
VI  - 5
IP  - 3
DP  - 2002 Jun 20
TI  - [Expression of GLUT1 protein and its relationship with uptake of FDG in non-small 
      cell lung cancer tissues].
PG  - 174-6
LID - 10.3779/j.issn.1009-3419.2002.03.05 [doi]
AB  - BACKGROUND: To investigate the expression of facilitative glucose transporter 1 
      (GLUT1) and its relationship with uptake of 18fluoro-2-deoxyglucose (FDG) in non 
      small cell lung cancer (NSCLC). METHODS: Twenty-four patients with NSCLC were 
      evaluated with 18FDG-PET examination before operation. The expression of GLUT1 
      was detected immunohistochemically in lung cancer and normal lung tissues, and 
      the intensity of GLUT1 in lung cancer was assessed by computer image analysis. 
      Correlation analysis was carried out between expression level of GLUT1 and value 
      of SUV obtained from preoperative FDG-PET. RESULTS: Expression of GLUT1 protein 
      was positive in 24 cases of NSCLC samples, but negative in corresponding normal 
      tissues. A highly significant linear correlation was found between GLUT1 
      expression and SUV value (r= 0.86, P < 0.05). CONCLUSIONS: GLUT1 expression is 
      quite general in NSCLC tissues, and it may play an important role in the glucose 
      uptake of NSCLC cells.
FAU - Wang, Kun
AU  - Wang K
AD  - Department of Thoracic Surgery, General Hospital of Beijing Unit,PLA, Beijing 
      100700, P.R.China.
FAU - Sun, Yu'e
AU  - Sun Y
FAU - Wang, Tao
AU  - Wang T
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhongguo Fei Ai Za Zhi
JT  - Zhongguo fei ai za zhi = Chinese journal of lung cancer
JID - 101126433
EDAT- 2002/06/20 00:00
MHDA- 2002/06/20 00:01
CRDT- 2011/02/18 06:00
PHST- 2011/02/18 06:00 [entrez]
PHST- 2002/06/20 00:00 [pubmed]
PHST- 2002/06/20 00:01 [medline]
AID - 10.3779/j.issn.1009-3419.2002.03.05 [doi]
PST - ppublish
SO  - Zhongguo Fei Ai Za Zhi. 2002 Jun 20;5(3):174-6. doi: 
      10.3779/j.issn.1009-3419.2002.03.05.