PMID- 21326679
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 0739-9529 (Print)
IS  - 1098-8963 (Electronic)
IS  - 0739-9529 (Linking)
VI  - 22
IP  - 2
DP  - 2005 Jun
TI  - Heparin in interventional radiology: a therapy in evolution.
PG  - 95-107
LID - 10.1055/s-2005-871864 [doi]
AB  - Interventional radiology techniques made possible by the antithrombotic 
      properties of heparin have revolutionized treatment for a myriad of disorders. 
      Newer low-molecular-weight heparins (LMWHs) offer several advantages over 
      unfractionated heparin (UFH), especially in chronic settings. They are increasing 
      in popularity for use during vascular procedures. However, LMWH shares 
      limitations with UFH such as heterogeneity, nonspecificity, and induction of 
      thrombocytopenia. These drawbacks have led to a search for the next generation of 
      antithrombotic agents. Homogeneous drugs targeting specific coagulation cascade 
      molecules are now available. The number of alternative anticoagulant drug 
      combinations presents clinicians with a confusing array of choices. The strengths 
      and weaknesses of UFH, LMWH, and direct antithrombin agents are presented. The 
      promising future of LMWH and hirudins is discussed.
FAU - Resnick, Stuart B
AU  - Resnick SB
AD  - Department of Radiology, New York Presbyterian/Columbia University Medical 
      Center, New York, New York.
FAU - Resnick, Stephanie H
AU  - Resnick SH
FAU - Weintraub, Joshua L
AU  - Weintraub JL
FAU - Kothary, Nishita
AU  - Kothary N
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Semin Intervent Radiol
JT  - Seminars in interventional radiology
JID - 8510974
PMC - PMC3036272
OTO - NOTNLM
OT  - Heparin
OT  - anticoagulation
OT  - bivalirudin
OT  - hirudin
OT  - interventional radiology
OT  - low-molecular-weight heparin
EDAT- 2005/06/01 00:00
MHDA- 2005/06/01 00:01
PMCR- 2006/06/01
CRDT- 2011/02/18 06:00
PHST- 2011/02/18 06:00 [entrez]
PHST- 2005/06/01 00:00 [pubmed]
PHST- 2005/06/01 00:01 [medline]
PHST- 2006/06/01 00:00 [pmc-release]
AID - 10.1055/s-2005-871864 [doi]
PST - ppublish
SO  - Semin Intervent Radiol. 2005 Jun;22(2):95-107. doi: 10.1055/s-2005-871864.