PMID- 21326953 OWN - NLM STAT- MEDLINE DCOM- 20110502 LR - 20211020 IS - 1449-1907 (Electronic) IS - 1449-1907 (Linking) VI - 8 IP - 2 DP - 2011 Feb 1 TI - Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction. PG - 106-13 AB - AIMS: Strain rate imaging techniques have been proposed for the detection of ischemic or viable myocardium in coronary artery disease, which is still a challenge in clinical cardiology. This retrospective comparative study analyzed regional left ventricular function and scaring with two-dimensional strain (2DS) in the first 4 to 10 days after acute anterior myocardial infarction (AMI). METHODS AND RESULTS: The study population consisted of 32 AMI patients with an LAD occlusion and successful reperfusion. The assessment of peak systolic 2DS and peak systolic strain rate (SR) was performed segment-oriented with the angle-independent speckle tracking algorithm Velocity Vector Imaging (VVI). The infarcted, adjacent and non-infarcted segments were revealed by late enhancement MRI (LE-MRI), which was used as reference for the comparison with 2DS. The infarcted segments showed a significant decrease of tissue velocities, 2DS and SR in comparison to the non-affected segments. CONCLUSION: 2DS and SR as assessed by VVI seem to be a suitable approach for echocardiographic quantification of global and regional myocardial function as well as a promising tool for multimodal risk stratification after anterior AMI. FAU - Butz, Thomas AU - Butz T AD - Department of Cardiology and Angiology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany. Thomas.Butz@Marienhospital-Herne.de FAU - Lang, Corinna N AU - Lang CN FAU - van Bracht, Marc AU - van Bracht M FAU - Prull, Magnus W AU - Prull MW FAU - Yeni, Hakan AU - Yeni H FAU - Maagh, Petra AU - Maagh P FAU - Plehn, Gunnar AU - Plehn G FAU - Meissner, Axel AU - Meissner A FAU - Trappe, Hans-Joachim AU - Trappe HJ LA - eng PT - Comparative Study PT - Journal Article DEP - 20110201 PL - Australia TA - Int J Med Sci JT - International journal of medical sciences JID - 101213954 SB - IM MH - Adult MH - Aged MH - Echocardiography, Doppler MH - Female MH - Humans MH - Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Myocardial Infarction/diagnostic imaging/*physiopathology MH - Retrospective Studies PMC - PMC3039226 OTO - NOTNLM OT - Late Enhancement MRI OT - Myocardial infarction OT - Strain rate imaging OT - Two-dimensional strain COIS- Conflict of Interest: The authors have declared that no conflict of interest exists. EDAT- 2011/02/18 06:00 MHDA- 2011/05/03 06:00 PMCR- 2011/01/01 CRDT- 2011/02/18 06:00 PHST- 2010/11/14 00:00 [received] PHST- 2011/01/31 00:00 [accepted] PHST- 2011/02/18 06:00 [entrez] PHST- 2011/02/18 06:00 [pubmed] PHST- 2011/05/03 06:00 [medline] PHST- 2011/01/01 00:00 [pmc-release] AID - ijmsv08p0106 [pii] AID - 10.7150/ijms.8.106 [doi] PST - epublish SO - Int J Med Sci. 2011 Feb 1;8(2):106-13. doi: 10.7150/ijms.8.106.