PMID- 21336356 OWN - NLM STAT- MEDLINE DCOM- 20110719 LR - 20131121 IS - 1364-548X (Electronic) IS - 1359-7345 (Linking) VI - 47 IP - 13 DP - 2011 Apr 7 TI - Single atom modification leads to enhanced nucleotide self-assembly: the role of cation bridging. PG - 3882-4 LID - 10.1039/c0cc05654e [doi] AB - We report that the ability of disodium 5'-deoxy-5'-thioguanosine-5'-monophosphate, Na(2)(5'-GSMP), to self-associate into a helical G-quadruplex structure in aqueous solution at pH 8 is significantly higher than that of disodium guanosine-5'-monophosphate, Na(2)(5'-GMP), which supports our earlier hypothesis regarding the importance of cation bridging. FAU - Kwan, Irene C M AU - Kwan IC AD - Department of Chemistry, Queen's University, 90 Bader Lane, Kingston, Ontario, Canada K7L 3N6. FAU - Delley, Richard J AU - Delley RJ FAU - Hodgson, David R W AU - Hodgson DR FAU - Wu, Gang AU - Wu G LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20110218 PL - England TA - Chem Commun (Camb) JT - Chemical communications (Cambridge, England) JID - 9610838 RN - 0 (Cations) RN - 12133JR80S (Guanosine) RN - 85-32-5 (Guanosine Monophosphate) SB - IM MH - Cations/chemistry MH - *G-Quadruplexes MH - Guanosine/*analogs & derivatives MH - Guanosine Monophosphate/*chemistry EDAT- 2011/02/22 06:00 MHDA- 2011/07/20 06:00 CRDT- 2011/02/22 06:00 PHST- 2011/02/22 06:00 [entrez] PHST- 2011/02/22 06:00 [pubmed] PHST- 2011/07/20 06:00 [medline] AID - 10.1039/c0cc05654e [doi] PST - ppublish SO - Chem Commun (Camb). 2011 Apr 7;47(13):3882-4. doi: 10.1039/c0cc05654e. Epub 2011 Feb 18.