PMID- 21339371 OWN - NLM STAT- MEDLINE DCOM- 20110617 LR - 20151119 IS - 1479-9731 (Electronic) IS - 1479-9723 (Linking) VI - 8 IP - 1 DP - 2011 TI - Effects of pulmonary rehabilitation in bronchiectasis: A retrospective study. PG - 21-30 LID - 10.1177/1479972310391282 [doi] AB - There is limited information about the benefits of pulmonary rehabilitation (PR) in patients with bronchiectasis. This study aimed to evaluate the effects of an out-patient PR program in patients with a primary diagnosis of bronchiectasis and to compare them with a matched COPD group who completed the same PR program. A retrospective review was conducted of patients with bronchiectasis or COPD who completed 6 to 8 weeks of PR at two tertiary institutions. The outcome measures were the 6-minute walk distance (6MWD) and Chronic Respiratory Disease Questionnaire (CRQ). Ninety-five patients with bronchiectasis completed the PR (48 male; FEV(1) 63 [24] % predicted; age 67 [10] years). Significant improvements in 6MWD (mean change 53.4 m, 95% CI 45.0 to 61.7) and CRQ total score (mean change 14.0 units, 95% CI 11.3 to 16.7) were observed immediately following PR. In patients with complete follow-up (n = 37), these improvements remained significantly higher than baseline at 12 months (20.5 m, 95% CI 1.4 to 39.5 for 6MWD; 12.1 points, 95% CI 5.7 to 18.4 for CRQ total score). The time trend and changes in the 6MWD and CRQ scores were not significantly different between the bronchiectasis and the COPD groups (all p > 0.05). This study supports the inclusion of patients with bronchiectasis in existing PR programs. Further prospective RCTs are warranted to substantiate these findings. FAU - Ong, H K AU - Ong HK AD - Physiotherapy, Melbourne School of Health Sciences, The University of Melbourne, Victoria, Australia. FAU - Lee, A L AU - Lee AL FAU - Hill, C J AU - Hill CJ FAU - Holland, A E AU - Holland AE FAU - Denehy, L AU - Denehy L LA - eng PT - Journal Article PL - England TA - Chron Respir Dis JT - Chronic respiratory disease JID - 101197408 SB - IM MH - Aged MH - Analysis of Variance MH - Bronchiectasis/*rehabilitation MH - Exercise Test MH - *Exercise Therapy MH - Exercise Tolerance/*physiology MH - Female MH - Forced Expiratory Volume/physiology MH - Humans MH - Male MH - Middle Aged MH - Patient Education as Topic MH - Pulmonary Disease, Chronic Obstructive/rehabilitation MH - Quality of Life MH - Retrospective Studies MH - Surveys and Questionnaires MH - Walking/*physiology EDAT- 2011/02/23 06:00 MHDA- 2011/06/18 06:00 CRDT- 2011/02/23 06:00 PHST- 2011/02/23 06:00 [entrez] PHST- 2011/02/23 06:00 [pubmed] PHST- 2011/06/18 06:00 [medline] AID - 8/1/21 [pii] AID - 10.1177/1479972310391282 [doi] PST - ppublish SO - Chron Respir Dis. 2011;8(1):21-30. doi: 10.1177/1479972310391282.