PMID- 21340775
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20110222
IS  - 1543-1894 (Print)
IS  - 1543-1894 (Linking)
VI  - 39
DP  - 2001
TI  - Interphase cytogenetics in frozen ovarian tumor tissue.
PG  - 215-21
LID - 10.1385/1-59259-071-3:215 [doi]
AB  - Resulting from problems of low yield of metaphases and poor-quality chromosomes, 
      detection of cytogenetic changes in solid tumors has been relatively limited (1). 
      The advent of fluorescence in situ hybridization (FISH) rendered it possible to 
      obtain "cytogenetic information" from interphase nuclei (2,3). Since that time, 
      interphase cytogenetics has become a powerful tool to investigate numerical 
      chromosomal aberrations (4,5), amplification of oncogenes (6), or deletion of 
      tumor suppressor genes in solid tumors (7), including ovarian cancer. Both fresh 
      tumor material (8-10) or formalin-fixed and, subsequently, paraffin-embedded 
      tissue have been used for interphase cytogenetic studies in ovarian tumors (4-6 
      8-10).
FAU - Liehr, T
AU  - Liehr T
AD  - Institut fur Humangenetik, Jena, Germany.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Methods Mol Med
JT  - Methods in molecular medicine
JID - 101123138
EDAT- 2001/01/01 00:00
MHDA- 2001/01/01 00:01
CRDT- 2011/02/23 06:00
PHST- 2011/02/23 06:00 [entrez]
PHST- 2001/01/01 00:00 [pubmed]
PHST- 2001/01/01 00:01 [medline]
AID - 10.1385/1-59259-071-3:215 [doi]
PST - ppublish
SO  - Methods Mol Med. 2001;39:215-21. doi: 10.1385/1-59259-071-3:215.