PMID- 21342230 OWN - NLM STAT- MEDLINE DCOM- 20110628 LR - 20221207 IS - 1346-8138 (Electronic) IS - 0385-2407 (Linking) VI - 38 IP - 3 DP - 2011 Mar TI - Stevens-Johnson syndrome induced by acetazolamide. PG - 272-5 LID - 10.1111/j.1346-8138.2010.00921.x [doi] AB - Acetazolamide is a sulfonamide derivative and carbonic anhydrase inhibitor used to lower intraocular pressure in glaucomatous patients. Stevens-Johnson syndrome (SJS) toxic epidermal necrolysis (TEN) associated with acetazolamide treatment has been diagnosed in Japanese, Japanese-American and Indian patients. Herein, we report the second Korean case of SJS-TEN associated with acetazolamide treatment. The result of human leukocyte antigen (HLA) typing of our patient was positive for HLA-B59. According to recent research, HLA-B59 has been detected in SJS caused by metazolamide, which is analogous to acetazolamide. This suggests a possible relationship between genetic background and SJS-TEN-associated acetazolamide treatment. Theretofore, acetazolamide should be prescribed to Korean patients with the same discreet caution. CI - (c) 2010 Japanese Dermatological Association. FAU - Her, Young AU - Her Y AD - Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea. FAU - Kil, Min S AU - Kil MS FAU - Park, Ju H AU - Park JH FAU - Kim, Chul W AU - Kim CW FAU - Kim, Sang S AU - Kim SS LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20101213 PL - England TA - J Dermatol JT - The Journal of dermatology JID - 7600545 RN - 0 (Carbonic Anhydrase Inhibitors) RN - 0 (HLA-B Antigens) RN - 0 (HLA-B59 antigen) RN - O3FX965V0I (Acetazolamide) SB - IM MH - Acetazolamide/*adverse effects MH - Adult MH - Asian People/*genetics MH - Carbonic Anhydrase Inhibitors/*adverse effects MH - Female MH - HLA-B Antigens/genetics MH - Humans MH - Stevens-Johnson Syndrome/*chemically induced/diagnosis/*ethnology/genetics EDAT- 2011/02/24 06:00 MHDA- 2011/06/29 06:00 CRDT- 2011/02/24 06:00 PHST- 2011/02/24 06:00 [entrez] PHST- 2011/02/24 06:00 [pubmed] PHST- 2011/06/29 06:00 [medline] AID - 10.1111/j.1346-8138.2010.00921.x [doi] PST - ppublish SO - J Dermatol. 2011 Mar;38(3):272-5. doi: 10.1111/j.1346-8138.2010.00921.x. Epub 2010 Dec 13.