PMID- 21344187
OWN - NLM
STAT- MEDLINE
DCOM- 20110816
LR  - 20121115
IS  - 1573-6814 (Electronic)
IS  - 1389-9333 (Linking)
VI  - 12
IP  - 2
DP  - 2011 May
TI  - Adeno-associated virus (AAV) based gene therapy for eye diseases.
PG  - 105-10
LID - 10.1007/s10561-011-9243-7 [doi]
AB  - Gene therapy emerged as important approach in treatment for many inborn disorders 
      caused by genetic defects, as well as other diseases. This manuscript focused on 
      Adeno-associated virus (AAV) based gene therapy to eye diseases. The paper 
      firstly introduced the AAV vectors and the techniques of eye delivery, then 
      summarized some tested genes that were used in past treatment to retinal 
      degeneration disorders. Finally the paper discussed the updated optogenetics and 
      its roles in AAV based gene therapy for eye diseases.
FAU - Wang, Shuang
AU  - Wang S
AD  - Department of Ophthalmology, The Second Hospital of Ji Lin University, 130041, Ji 
      Lin, China.
FAU - Liu, Peng
AU  - Liu P
FAU - Song, Lei
AU  - Song L
FAU - Lu, Lei
AU  - Lu L
FAU - Zhang, Wensong
AU  - Zhang W
FAU - Wu, Yazhen
AU  - Wu Y
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20110223
PL  - Netherlands
TA  - Cell Tissue Bank
JT  - Cell and tissue banking
JID - 100965121
SB  - IM
MH  - Animals
MH  - Dependovirus/*genetics
MH  - Eye/metabolism/pathology
MH  - Eye Diseases/genetics/pathology/*therapy
MH  - Gene Transfer Techniques
MH  - Genetic Therapy/*methods
MH  - Genetic Vectors/genetics
MH  - Humans
EDAT- 2011/02/24 06:00
MHDA- 2011/08/17 06:00
CRDT- 2011/02/24 06:00
PHST- 2010/12/12 00:00 [received]
PHST- 2011/02/04 00:00 [accepted]
PHST- 2011/02/24 06:00 [entrez]
PHST- 2011/02/24 06:00 [pubmed]
PHST- 2011/08/17 06:00 [medline]
AID - 10.1007/s10561-011-9243-7 [doi]
PST - ppublish
SO  - Cell Tissue Bank. 2011 May;12(2):105-10. doi: 10.1007/s10561-011-9243-7. Epub 
      2011 Feb 23.