PMID- 21345648
OWN - NLM
STAT- MEDLINE
DCOM- 20110901
LR  - 20220330
IS  - 1097-6795 (Electronic)
IS  - 0894-7317 (Linking)
VI  - 24
IP  - 5
DP  - 2011 May
TI  - Echocardiographic indices of diastolic function relate to functional capacity and 
      quality of life in ambulatory men with atrial fibrillation.
PG  - 533-540.e3
LID - 10.1016/j.echo.2011.01.008 [doi]
AB  - OBJECTIVE: We sought to explore the reliability of echocardiographic parameters 
      of diastolic function and determine their relationship with functional capacity 
      (New York Heart Association [NYHA] class and 6-minute walk test [6MWT]) and the 
      domains of a health-related quality of life (HR-QOL) questionnaire (Veterans RAND 
      36-Item Health Survey) in a cohort of ambulatory patients with atrial 
      fibrillation (AF). METHODS: Forty-eight male veterans with persistent or 
      permanent AF underwent clinical examination, echocardiography, and 6MWT, and 
      filled out a Veterans RAND 36-Item Health Survey questionnaire at two visits 1 
      week apart. Pairwise correlation was performed to evaluate the reliability of 
      echocardiographic parameters and multiple regression analyses to assess the 
      association of these parameters with functional capacity and HR-QOL. RESULTS: 
      E/e' average had the highest correlation between the two visits (coefficient: 
      0.87) and had a significant relationship with NYHA, 6MWT, and physical 
      functioning domain of HR-QOL even after adjusting for confounding variables (odds 
      of NYHA >1: OR 1.5, 95% CI, 1.2-1.9; 6MWT coefficient: -31 +/- 9 ft; physical 
      functioning score coefficient: -1.7 +/- 0.7). CONCLUSION: Average E/e' is a 
      reliable diastolic function parameter that also independently relates with 
      functional capacity and HR-QOL in ambulatory patients with atrial fibrillation.
CI  - Published by Mosby, Inc.
FAU - Punjani, Shahnaz
AU  - Punjani S
AD  - Vascular Research Laboratory, Providence VA Medical Center, Providence, Rhode 
      Island 02908, USA.
FAU - Wu, Wen-Chih
AU  - Wu WC
FAU - Cohen, Scott
AU  - Cohen S
FAU - Sharma, Satish C
AU  - Sharma SC
FAU - Choudhary, Gaurav
AU  - Choudhary G
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Validation Study
DEP - 20110222
PL  - United States
TA  - J Am Soc Echocardiogr
JT  - Journal of the American Society of Echocardiography : official publication of the 
      American Society of Echocardiography
JID - 8801388
SB  - IM
MH  - Acceleration
MH  - Aged
MH  - Atrial Fibrillation/*diagnostic imaging/pathology/psychology
MH  - Confidence Intervals
MH  - Diastole
MH  - Echocardiography, Doppler
MH  - Exercise Test
MH  - Health Services
MH  - Health Status Indicators
MH  - Humans
MH  - Male
MH  - Odds Ratio
MH  - *Quality of Life
MH  - Reproducibility of Results
MH  - Statistics as Topic
MH  - Surveys and Questionnaires
MH  - Veterans
MH  - *Walking
EDAT- 2011/02/25 06:00
MHDA- 2011/09/02 06:00
CRDT- 2011/02/25 06:00
PHST- 2010/07/29 00:00 [received]
PHST- 2011/02/25 06:00 [entrez]
PHST- 2011/02/25 06:00 [pubmed]
PHST- 2011/09/02 06:00 [medline]
AID - S0894-7317(11)00041-1 [pii]
AID - 10.1016/j.echo.2011.01.008 [doi]
PST - ppublish
SO  - J Am Soc Echocardiogr. 2011 May;24(5):533-540.e3. doi: 
      10.1016/j.echo.2011.01.008. Epub 2011 Feb 22.