PMID- 21347598
OWN - NLM
STAT- MEDLINE
DCOM- 20120619
LR  - 20211020
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Print)
IS  - 1569-5794 (Linking)
VI  - 28
IP  - 2
DP  - 2012 Feb
TI  - Cardiac magnetic resonance visualizes acute and chronic myocardial injuries in 
      myocarditis.
PG  - 327-35
LID - 10.1007/s10554-011-9812-7 [doi]
AB  - Our objective was to evaluate the ability of CMR to visualize myocardial injuries 
      over the course of myocarditis. We studied 42 patients (39 males, 3 females; age 
      37 +/- 14 years) with myocarditis during the acute phase and after 12 +/- 9 months. 
      CMR included function analyses, T2-weighted imaging (T2 ratio), T1-weighted 
      imaging before and after i.v. gadolinium injection (global relative enhancement; 
      gRE), and late gadolinium enhancement (LGE). In the acute phase, the T2 ratio was 
      elevated in 57%, gRE in 31%, and LGE was present in 64% of the patients. In 32 
      patients (76%) were any two (or more) out of three sequences abnormal. At 
      follow-up, there was an increase in ejection fraction (57.4 +/- 11.9% vs. 
      61.4 +/- 7.6; P < 0.05) while both T2 ratio (2.04 +/- 0.32 vs. 1.70 +/- 0.28; 
      P < 0.001) and gRE (4.07 +/- 1.63 vs. 3.11 +/- 1.22; P < 0.05) significantly 
      decreased. The LGE persisted in 10 patients. Dilated cardiomyopathy was present 
      in 3 patients and 4 patients received a defibrillator or a pacemaker. A 
      comprehensive CMR approach is a useful tool to visualize myocardial tissue 
      injuries over the course of myocarditis. CMR may help to differentiate acute from 
      healed myocarditis, and add information for the differential diagnoses.
FAU - Stensaeth, Knut Haakon
AU  - Stensaeth KH
AD  - Department of Radiology, Oslo University Hospital, Ullevaal, Oslo, Norway. 
      k.h.stensath@medisin.uio.no
FAU - Hoffmann, Pavel
AU  - Hoffmann P
FAU - Fossum, Eigil
AU  - Fossum E
FAU - Mangschau, Arild
AU  - Mangschau A
FAU - Sandvik, Leiv
AU  - Sandvik L
FAU - Klow, Nils Einar
AU  - Klow NE
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20110224
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Chi-Square Distribution
MH  - Contrast Media
MH  - Diagnosis, Differential
MH  - Female
MH  - Gadolinium DTPA
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocarditis/complications/*diagnosis/pathology/physiopathology
MH  - Myocardium/*pathology
MH  - Norway
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - Time Factors
MH  - Ventricular Function, Left
MH  - Young Adult
PMC - PMC3288366
EDAT- 2011/02/25 06:00
MHDA- 2012/06/20 06:00
PMCR- 2011/02/24
CRDT- 2011/02/25 06:00
PHST- 2010/10/05 00:00 [received]
PHST- 2011/01/17 00:00 [accepted]
PHST- 2011/02/25 06:00 [entrez]
PHST- 2011/02/25 06:00 [pubmed]
PHST- 2012/06/20 06:00 [medline]
PHST- 2011/02/24 00:00 [pmc-release]
AID - 9812 [pii]
AID - 10.1007/s10554-011-9812-7 [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2012 Feb;28(2):327-35. doi: 10.1007/s10554-011-9812-7. 
      Epub 2011 Feb 24.