PMID- 21349102
OWN - NLM
STAT- MEDLINE
DCOM- 20110922
LR  - 20110225
IS  - 1348-0421 (Electronic)
IS  - 0385-5600 (Linking)
VI  - 55
IP  - 3
DP  - 2011 Mar
TI  - Genetic analysis of ORF5 in porcine reproductive and respiratory syndrome virus 
      in Japan.
PG  - 211-6
LID - 10.1111/j.1348-0421.2010.00303.x [doi]
AB  - In recent years, no reports regarding genetic information on porcine reproductive 
      and respiratory syndrome virus (PRRSV) with a focus on Japan have been published. 
      To clarify the effect of time on PRRSV genomic evolution, we sequenced the open 
      reading frame 5 (600 or 603 bases) obtained from Japanese PRRSV isolates for 
      three periods (1992-1993, 2000-2001, and 2007-2008) and compared their 
      phylogenetic relationships. Assessment of mean pairwise homology of nucleotide 
      sequences of PRRSV isolates indicated a trend towards increasing heterogeneity 
      over time. In addition, we newly detected a virus classified in cluster IV, 
      indicative of the increasing genetic variation of PRRSV in Japan.
CI  - (c) 2011 The Societies and Blackwell Publishing Asia Pty Ltd.
FAU - Iseki, Hiroshi
AU  - Iseki H
AD  - Viral Diseases Research Team, National Institute of Animal Health, Tsukuba, 
      Ibaraki, Japan.
FAU - Takagi, Michihiro
AU  - Takagi M
FAU - Miyazaki, Ayako
AU  - Miyazaki A
FAU - Katsuda, Ken
AU  - Katsuda K
FAU - Mikami, Osamu
AU  - Mikami O
FAU - Tsunemitsu, Hiroshi
AU  - Tsunemitsu H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Australia
TA  - Microbiol Immunol
JT  - Microbiology and immunology
JID - 7703966
RN  - 0 (Viral Proteins)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Evolution, Molecular
MH  - *Genetic Variation
MH  - Japan
MH  - Molecular Sequence Data
MH  - Open Reading Frames/*genetics
MH  - Phylogeny
MH  - Porcine respiratory and reproductive syndrome virus/classification/*genetics
MH  - Sequence Alignment
MH  - Sequence Homology
MH  - Swine
MH  - Viral Proteins/*genetics
EDAT- 2011/02/26 06:00
MHDA- 2011/09/23 06:00
CRDT- 2011/02/26 06:00
PHST- 2011/02/26 06:00 [entrez]
PHST- 2011/02/26 06:00 [pubmed]
PHST- 2011/09/23 06:00 [medline]
AID - 10.1111/j.1348-0421.2010.00303.x [doi]
PST - ppublish
SO  - Microbiol Immunol. 2011 Mar;55(3):211-6. doi: 10.1111/j.1348-0421.2010.00303.x.