PMID- 21354354
OWN - NLM
STAT- MEDLINE
DCOM- 20120110
LR  - 20110718
IS  - 1878-1705 (Electronic)
IS  - 1567-5769 (Linking)
VI  - 11
IP  - 8
DP  - 2011 Aug
TI  - Antigen in chitosan coated liposomes enhances immune responses through parenteral 
      immunization.
PG  - 907-14
LID - 10.1016/j.intimp.2011.02.002 [doi]
AB  - To overcome the limitations of the use of conventional liposomes chitosan coated 
      egg yolk lecithin based liposomes were used as antigen carrier through parenteral 
      administration in two animal models such as fish and rabbit. Extracellular 
      proteins (ECPs) antigen of Aeromonas hydrophila encapsulated in liposomes became 
      more stable and induced better immune response. It enhanced both adaptive and 
      innate immune responses than other preparations both at 21, 42 and 63days 
      post-immunization and suggested to be a better antigen delivery system.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Behera, T
AU  - Behera T
AD  - Fish Health Management Division, Central Institute of Freshwater Aquaculture, 
      Kausalyaganga, Bhubaneswar-751 002, Orissa, India.
FAU - Swain, P
AU  - Swain P
FAU - Sahoo, S K
AU  - Sahoo SK
LA  - eng
PT  - Journal Article
DEP - 20110224
PL  - Netherlands
TA  - Int Immunopharmacol
JT  - International immunopharmacology
JID - 100965259
RN  - 0 (Antibodies)
RN  - 0 (Antigens, Bacterial)
RN  - 0 (Lecithins)
RN  - 0 (Liposomes)
RN  - 9012-76-4 (Chitosan)
SB  - IM
MH  - Aeromonas hydrophila
MH  - Animals
MH  - Antibodies/immunology
MH  - Antigens, Bacterial/*administration & dosage/chemistry/*immunology
MH  - Chitosan/administration & dosage/*chemistry
MH  - Egg Yolk/chemistry
MH  - Fishes
MH  - Immunity, Innate/drug effects/immunology
MH  - Immunization/*methods
MH  - Infusions, Parenteral/methods
MH  - Lecithins/administration & dosage
MH  - Liposomes/administration & dosage/*chemistry
MH  - Rabbits
EDAT- 2011/03/01 06:00
MHDA- 2012/01/11 06:00
CRDT- 2011/03/01 06:00
PHST- 2010/12/09 00:00 [received]
PHST- 2011/01/22 00:00 [revised]
PHST- 2011/02/01 00:00 [accepted]
PHST- 2011/03/01 06:00 [entrez]
PHST- 2011/03/01 06:00 [pubmed]
PHST- 2012/01/11 06:00 [medline]
AID - S1567-5769(11)00073-7 [pii]
AID - 10.1016/j.intimp.2011.02.002 [doi]
PST - ppublish
SO  - Int Immunopharmacol. 2011 Aug;11(8):907-14. doi: 10.1016/j.intimp.2011.02.002. 
      Epub 2011 Feb 24.