PMID- 21354741
OWN - NLM
STAT- MEDLINE
DCOM- 20110721
LR  - 20220321
IS  - 1873-264X (Electronic)
IS  - 0731-7085 (Linking)
VI  - 55
IP  - 3
DP  - 2011 Jun 1
TI  - Development of the chromatographic  fi ngerprint of Scutellaria barbata D. Don by 
      GC-MS combined with Chemometrics methods.
PG  - 391-6
LID - 10.1016/j.jpba.2011.01.016 [doi]
AB  - Gas chromatography fingerprint of Scutellaria barbata D. Don (SB) from different 
      origins was studied by gas chromatography-mass spectrometry (GC-MS) and related 
      Chemometrics methods. The constituents of essential oil of Scutellaria barbata D. 
      Don (SB) and its two adulterants Oldenlandia diffusa (OD) and Lobelia chinensis 
      Lour (LCL) were analyzed and compared, 50, 36 and 38 components were identified 
      from SB, OD and LCL, respectively, there were 16 and 18 common components between 
      SB and OD, SB and LCL. Nine different samples collected from different producing 
      areas of SB were studied. The relative standard deviations (RSDs) of retention 
      time and peak area of each component were less than 0.2% and 6%, respectively. 
      The number of common peaks was up to 52 and the un-common peak area was less than 
      10%. The similarity and difference among SB and its adulterants were also 
      evaluated by correlation coefficient similarity analysis and principal component 
      analysis, the result showed that developed fingerprint characterize the SB from 
      different producing areas and it is useful and feasible for the discrimination of 
      its adulterants.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Pan, Ruijing
AU  - Pan R
AD  - Research Center of Modernization of Chinese Herbal Medicine, College of Chemistry 
      and Chemical Engineering, Central South University, Changsha, Hunan, PR China.
FAU - Guo, Fangqiu
AU  - Guo F
FAU - Lu, Hongmei
AU  - Lu H
FAU - Feng, Wei-Wei
AU  - Feng WW
FAU - Liang, Yi-Zeng
AU  - Liang YZ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110122
PL  - England
TA  - J Pharm Biomed Anal
JT  - Journal of pharmaceutical and biomedical analysis
JID - 8309336
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Oils, Volatile)
RN  - 0 (Plant Oils)
SB  - IM
MH  - China
MH  - Drugs, Chinese Herbal/*analysis/standards
MH  - Gas Chromatography-Mass Spectrometry/instrumentation/*methods
MH  - Lobelia/chemistry/growth & development
MH  - Oils, Volatile/*analysis
MH  - Oldenlandia/chemistry/growth & development
MH  - Plant Oils/*analysis
MH  - Principal Component Analysis
MH  - Quality Control
MH  - Reproducibility of Results
MH  - Scutellaria/*chemistry/growth & development
EDAT- 2011/03/01 06:00
MHDA- 2011/07/22 06:00
CRDT- 2011/03/01 06:00
PHST- 2010/10/14 00:00 [received]
PHST- 2011/01/04 00:00 [revised]
PHST- 2011/01/17 00:00 [accepted]
PHST- 2011/03/01 06:00 [entrez]
PHST- 2011/03/01 06:00 [pubmed]
PHST- 2011/07/22 06:00 [medline]
AID - S0731-7085(11)00041-0 [pii]
AID - 10.1016/j.jpba.2011.01.016 [doi]
PST - ppublish
SO  - J Pharm Biomed Anal. 2011 Jun 1;55(3):391-6. doi: 10.1016/j.jpba.2011.01.016. 
      Epub 2011 Jan 22.