PMID- 21354802
OWN - NLM
STAT- MEDLINE
DCOM- 20110823
LR  - 20131121
IS  - 1872-9800 (Electronic)
IS  - 0969-8043 (Linking)
VI  - 69
IP  - 7
DP  - 2011 Jul
TI  - Determination of boron concentration in blood and tissue samples from patients 
      with liver metastases of colorectal carcinoma using Prompt Gamma Ray Activation 
      Analysis (PGAA).
PG  - 936-41
LID - 10.1016/j.apradiso.2011.02.007 [doi]
AB  - As part of the studies on Boron Neutron Capture Therapy at the University of 
      Mainz, Germany, a clinical trial has been started in which, four patients 
      suffering from liver metastases of colorectal carcinoma have been enrolled. 
      Specimens of blood and healthy tissue samples taken from the patients were 
      measured at the PGAA facilities at the HFR in Petten, The Netherlands, and at the 
      FRM II in Munich, Germany. From the measured boron concentrations, 
      pharmacokinetic curves and blood-to-tissue concentration ratios were produced.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Schmitz, T
AU  - Schmitz T
AD  - Institute for Nuclear Chemistry, University of Mainz, Fritz-Strassmann-Weg 2, 
      Mainz, Germany. schmito@uni-mainz.de
FAU - Appelman, K
AU  - Appelman K
FAU - Kudejova, P
AU  - Kudejova P
FAU - Schutz, C
AU  - Schutz C
FAU - Kratz, J V
AU  - Kratz JV
FAU - Moss, R
AU  - Moss R
FAU - Otto, G
AU  - Otto G
FAU - Hampel, G
AU  - Hampel G
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110212
PL  - England
TA  - Appl Radiat Isot
JT  - Applied radiation and isotopes : including data, instrumentation and methods for 
      use in agriculture, industry and medicine
JID - 9306253
RN  - N9E3X5056Q (Boron)
SB  - IM
MH  - Boron/blood/*metabolism
MH  - Colorectal Neoplasms/blood/*pathology
MH  - Humans
MH  - Liver Neoplasms/blood/*secondary/surgery
EDAT- 2011/03/01 06:00
MHDA- 2011/08/24 06:00
CRDT- 2011/03/01 06:00
PHST- 2010/08/27 00:00 [received]
PHST- 2011/01/26 00:00 [revised]
PHST- 2011/02/04 00:00 [accepted]
PHST- 2011/03/01 06:00 [entrez]
PHST- 2011/03/01 06:00 [pubmed]
PHST- 2011/08/24 06:00 [medline]
AID - S0969-8043(11)00082-0 [pii]
AID - 10.1016/j.apradiso.2011.02.007 [doi]
PST - ppublish
SO  - Appl Radiat Isot. 2011 Jul;69(7):936-41. doi: 10.1016/j.apradiso.2011.02.007. 
      Epub 2011 Feb 12.