PMID- 21355145
OWN - NLM
STAT- MEDLINE
DCOM- 20110322
LR  - 20110228
IS  - 0255-2930 (Print)
IS  - 0255-2930 (Linking)
VI  - 31
IP  - 1
DP  - 2011 Jan
TI  - [Acupuncture for chronic pelvic pain syndromes (CPPS) and its effect on cytokines 
      in prostatic fluid].
PG  - 11-4
AB  - OBJECTIVE: To explore the effect of acupuncture on chronic pelvic pain syndromes 
      (CPPS), and its therapeutic mechanism. METHODS: Fourty-seven cases of CPPS were 
      treated with electroacupuncture on Zhongji (CV 3), Guilai (ST 29), Yinlingquan 
      (SP 9), Sanyinjiao (SP 6), Guanyuan (CV 4), Shuidao(ST 28), Xuehai (SP 10) and 
      Taichong (LR 3) as main acupoints. Chronic Prostatitis Symptom Index (CPSI) was 
      adopted to grade the severity of pain or discomforts. Additionally, the levels of 
      Interleukin-8 (IL-8), Interleukin-10 (IL-10) and Tumor necrosis factor-alpha 
      (TNF-alpha) in prostate fluid were detected and the correlation between those 
      changes and pain score was analyzed. RESULTS: After treatment, pain or discomfort 
      score in CPSI decreased remarkably as compared with that before treatment (P < 
      0.01). The levels of IL-8, IL-10 and TNF-alpha were lower than those before 
      treatment (P < 0.01, P < 0.05). The positive correlation was obtained between 
      IL-10 level and pain score (P < 0.05). The total effective rate was 89.4% 
      (42/47). CONCLUSION: Acupuncture has significant efficacy on CPPS through 
      reducing IL-10 level to ease pain, and reducing the levels of IL-8 and TNF-alpha 
      to relieve inflammatory reaction.
FAU - Yuan, Shao-Ying
AU  - Yuan SY
AD  - Male Department of Zhuhai Branch of Guangdong Provincial TCM Hospital, Zhuhai 
      519000, China. ysy017@126.com
FAU - Qin, Zhan
AU  - Qin Z
FAU - Liu, Dong-Sheng
AU  - Liu DS
FAU - Yin, Wei-Qiang
AU  - Yin WQ
FAU - Zhang, Zhao-Lei
AU  - Zhang ZL
FAU - Li, Shen-Guo
AU  - Li SG
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhongguo Zhen Jiu
JT  - Zhongguo zhen jiu = Chinese acupuncture & moxibustion
JID - 8600658
RN  - 0 (Interleukin-8)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 130068-27-8 (Interleukin-10)
SB  - IM
MH  - Acupuncture Points
MH  - *Acupuncture Therapy
MH  - Adult
MH  - Body Fluids/*immunology
MH  - Chronic Disease/therapy
MH  - Humans
MH  - Interleukin-10/immunology
MH  - Interleukin-8/immunology
MH  - Male
MH  - Middle Aged
MH  - Pelvic Pain/*immunology/*therapy
MH  - Prostate/*immunology
MH  - Tumor Necrosis Factor-alpha/immunology
MH  - Young Adult
EDAT- 2011/03/02 06:00
MHDA- 2011/03/23 06:00
CRDT- 2011/03/02 06:00
PHST- 2011/03/02 06:00 [entrez]
PHST- 2011/03/02 06:00 [pubmed]
PHST- 2011/03/23 06:00 [medline]
PST - ppublish
SO  - Zhongguo Zhen Jiu. 2011 Jan;31(1):11-4.