PMID- 21357135
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20200929
IS  - 1559-6095 (Linking)
VI  - 2007
DP  - 2007 Jul 1
TI  - Using the Basic Local Alignment Search Tool (BLAST).
PG  - pdb.top17
LID - 2007/7/pdb.top17 [pii]
LID - 10.1101/pdb.top17 [doi]
AB  - INTRODUCTIONThe BLAST algorithm was developed as a way to perform DNA and protein 
      sequence similarity searches by an algorithm that is faster than FASTA but 
      considered to be equally as sensitive. Both of these methods follow a heuristic 
      (tried-and-true) method that almost always works to find related sequences in a 
      database search, but does not have the underlying guarantee of an optimal 
      solution like the dynamic programming algorithm. FASTA finds short common 
      patterns in query and database sequences and joins these into an alignment. BLAST 
      is similar to FASTA, but gains a further increase in speed by searching only for 
      rarer, more significant patterns in nucleic acid and protein sequences. BLAST is 
      very popular due to its availability on the World Wide Web through a large server 
      at the National Center for Biotechnology Information (NCBI) and at many other 
      sites. The BLAST algorithm has evolved to provide molecular biologists with a set 
      of very powerful search tools that are freely available to run on many computer 
      platforms. This article is intended to be a "user's guide" to the principles 
      underlying BLAST.
FAU - Mount, David W
AU  - Mount DW
LA  - eng
PT  - Journal Article
DEP - 20070701
PL  - United States
TA  - CSH Protoc
JT  - CSH protocols
JID - 101280522
EDAT- 2007/01/01 00:00
MHDA- 2007/01/01 00:01
CRDT- 2011/03/02 06:00
PHST- 2011/03/02 06:00 [entrez]
PHST- 2007/01/01 00:00 [pubmed]
PHST- 2007/01/01 00:01 [medline]
AID - 2007/7/pdb.top17 [pii]
AID - 10.1101/pdb.top17 [doi]
PST - epublish
SO  - CSH Protoc. 2007 Jul 1;2007:pdb.top17. doi: 10.1101/pdb.top17.