PMID- 21359138 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211020 IS - 0018-9197 (Print) IS - 0018-9197 (Linking) VI - 16 IP - 3 DP - 2010 Jun 3 TI - Intravascular Photoacoustic Imaging. PG - 588-599 AB - Intravascular photoacoustic (IVPA) imaging is a catheter-based, minimally invasive, imaging modality capable of providing high-resolution optical absorption map of the arterial wall. Integrated with intravascular ultrasound (IVUS) imaging, combined IVPA and IVUS imaging can be used to detect and characterize atherosclerotic plaques building up in the inner lining of an artery. In this paper, we present and discuss various representative applications of combined IVPA/IVUS imaging of atherosclerosis, including assessment of the composition of atherosclerotic plaques, imaging of macrophages within the plaques, and molecular imaging of biomarkers associated with formation and development of plaques. In addition, imaging of coronary artery stents using IVPA and IVUS imaging is demonstrated. Furthermore, the design of an integrated IVUS/IVPA imaging catheter needed for in vivo clinical applications is discussed. FAU - Wang, Bo AU - Wang B AD - Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712 USA. FAU - Su, Jimmy L AU - Su JL FAU - Karpiouk, Andrei B AU - Karpiouk AB FAU - Sokolov, Konstantin V AU - Sokolov KV FAU - Smalling, Richard W AU - Smalling RW FAU - Emelianov, Stanislav Y AU - Emelianov SY LA - eng GR - R01 HL096981/HL/NHLBI NIH HHS/United States GR - R21 HL084076/HL/NHLBI NIH HHS/United States GR - R21 HL084076-01A2/HL/NHLBI NIH HHS/United States GR - R21 HL084076-02/HL/NHLBI NIH HHS/United States PT - Journal Article PL - United States TA - IEEE J Quantum Electron JT - IEEE journal of quantum electronics JID - 101204403 PMC - PMC3045110 MID - NIHMS270117 EDAT- 2011/03/02 06:00 MHDA- 2011/03/02 06:01 PMCR- 2011/02/25 CRDT- 2011/03/02 06:00 PHST- 2011/03/02 06:00 [entrez] PHST- 2011/03/02 06:00 [pubmed] PHST- 2011/03/02 06:01 [medline] PHST- 2011/02/25 00:00 [pmc-release] AID - 10.1109/JSTQE.2009.2037023 [doi] PST - ppublish SO - IEEE J Quantum Electron. 2010 Jun 3;16(3):588-599. doi: 10.1109/JSTQE.2009.2037023.