PMID- 21360753
OWN - NLM
STAT- MEDLINE
DCOM- 20131209
LR  - 20130509
IS  - 1099-1166 (Electronic)
IS  - 0885-6230 (Linking)
VI  - 26
IP  - 11
DP  - 2011 Nov
TI  - Detection and treatment of post stroke depression: results from the registry of 
      the Canadian stroke network.
PG  - 1195-200
LID - 10.1002/gps.2663 [doi]
AB  - BACKGROUND: Depression occurs in approximately one-third of patients following 
      stroke based on studies that screen entire stroke populations. Less is known 
      about the detection and treatment of post stroke depression (PSD) in routine 
      clinical practice. METHODS: This was a prospective cohort study of 7643 
      consecutive stroke patients >66 years of age, from 13 designated stroke centres 
      in Ontario, Canada. PSD was defined as (a) presence of strong evidence of 
      depression documented in the patient chart plus a prescribed antidepressant and a 
      psychiatric consult, or (b) prescription of a new antidepressant following 
      admission. The prevalence of PSD was determined and patients with and without PSD 
      were compared on a variety of measures. Patients admitted to specialized stroke 
      units were compared to patients admitted to standard units in order to determine 
      if PSD detection and treatment rates differed. RESULTS: PSD was diagnosed in 
      4.8%, and 6.7% were treated with a new antidepressant. Patients with PSD had more 
      severe strokes, more functional handicap, longer hospital stays and were less 
      likely to be discharged home (all p < 0.001). Patients admitted to specialized 
      stroke units were more likely to be diagnosed with depression (5.2% vs 4.0%, 
      p < 0.014) and were more likely to receive a new prescription for an 
      antidepressant (7.8% vs 4.5%; p < 0.001). CONCLUSIONS: Rates of diagnosed and 
      treated PSD in routine clinical practice are low and appear significantly lower 
      than those from studies that utilize active screening of entire stroke 
      populations. These results support the routine screening of all patients for PSD 
      using validated instruments. Specialized stroke unit care may improve PSD 
      detection and treatment rates.
CI  - Copyright (c) 2011 John Wiley & Sons, Ltd.
FAU - Herrmann, Nathan
AU  - Herrmann N
AD  - Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, 
      Canada. n.herrmann@utoronto.ca
FAU - Seitz, Dallas
AU  - Seitz D
FAU - Fischer, Hadas
AU  - Fischer H
FAU - Saposnik, Gustavo
AU  - Saposnik G
FAU - Calzavara, Andrew
AU  - Calzavara A
FAU - Anderson, Geoff
AU  - Anderson G
FAU - Rochon, Paula
AU  - Rochon P
LA  - eng
GR  - Canadian Institutes of Health Research/Canada
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110301
PL  - England
TA  - Int J Geriatr Psychiatry
JT  - International journal of geriatric psychiatry
JID - 8710629
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Analysis of Variance
MH  - Antidepressive Agents/therapeutic use
MH  - Canada/epidemiology
MH  - Depressive Disorder/diagnosis/drug therapy/*epidemiology/etiology
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Length of Stay
MH  - Male
MH  - Mass Screening/statistics & numerical data
MH  - Prevalence
MH  - Prospective Studies
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stroke/*psychology
EDAT- 2011/03/02 06:00
MHDA- 2013/12/16 06:00
CRDT- 2011/03/02 06:00
PHST- 2010/07/09 00:00 [received]
PHST- 2010/10/25 00:00 [accepted]
PHST- 2011/03/02 06:00 [entrez]
PHST- 2011/03/02 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 10.1002/gps.2663 [doi]
PST - ppublish
SO  - Int J Geriatr Psychiatry. 2011 Nov;26(11):1195-200. doi: 10.1002/gps.2663. Epub 
      2011 Mar 1.