PMID- 21375579
OWN - NLM
STAT- MEDLINE
DCOM- 20110811
LR  - 20181201
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 28
IP  - 3
DP  - 2011 Mar
TI  - Examination of hyperlucent foci and clinical outcomes in pediatric cardiac 
      patients on extracorporeal membrane oxygenation.
PG  - 358-62
LID - 10.1111/j.1540-8175.2010.01339.x [doi]
AB  - BACKGROUND: A number of cardiac patients on venoarterial extracorporeal membrane 
      oxygenation (VA-ECMO) at our institution were found to have hyperlucent foci 
      evident on echocardiography. However, the clinical significance of these findings 
      is not known. METHODS: To investigate this phenomenon further we undertook a 
      retrospective analysis to determine the prevalence and clinical implications of 
      hyperlucent foci in children supported with VA-ECMO. RESULTS: From January 2002 
      to September 2009 49 subjects were supported with VA-ECMO. Of these, 12 (24%) 
      were found to have hyperlucent foci. Foci were multifocal in six subjects (50%) 
      and the most common location was left ventricular wall. No association was noted 
      between primary cardiac diagnoses, or for inciting reason for placement on ECMO 
      (extracorporeal cardiopulmonary resuscitation vs. transition from cardiopulmonary 
      bypass to ECMO). There was no association between the presence of the foci and 
      death in less than 14 days following decannulation from ECMO, hospital survival 
      42% versus 43%, P = 0.1. Among subjects who survived at least 14 days after ECMO 
      decannulation hyperlucent foci resolved in 5 of 7. CONCLUSIONS: Hyperlucent foci 
      can be seen in children supported by VA-ECMO. They do not portend a poorer 
      prognosis. Among hospital survivors resolution is the norm.
CI  - (c) 2011, Wiley Periodicals, Inc.
FAU - Brothers, Matthew
AU  - Brothers M
AD  - Department of Pediatrics, Emory University School of Medicine, Sibley Heart 
      Center at Children's Healthcare of Atlanta, Atlanta, Georgia 30322-1062, USA.
FAU - Kreeger, Joseph
AU  - Kreeger J
FAU - Mahle, William T
AU  - Mahle WT
LA  - eng
PT  - Journal Article
DEP - 20110307
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Extracorporeal Membrane Oxygenation/*statistics & numerical data
MH  - Female
MH  - Georgia/epidemiology
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Prevalence
MH  - Risk Assessment
MH  - Risk Factors
MH  - Treatment Outcome
MH  - Ultrasonography
MH  - Ventricular Dysfunction, Left/*diagnostic imaging/*epidemiology
EDAT- 2011/03/08 06:00
MHDA- 2011/08/13 06:00
CRDT- 2011/03/08 06:00
PHST- 2011/03/08 06:00 [entrez]
PHST- 2011/03/08 06:00 [pubmed]
PHST- 2011/08/13 06:00 [medline]
AID - 10.1111/j.1540-8175.2010.01339.x [doi]
PST - ppublish
SO  - Echocardiography. 2011 Mar;28(3):358-62. doi: 10.1111/j.1540-8175.2010.01339.x. 
      Epub 2011 Mar 7.