PMID- 21381417
OWN - NLM
STAT- MEDLINE
DCOM- 20120213
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 28
IP  - 11
DP  - 2010 Nov
TI  - [Determination of cyanuric acid in milk and milk powder by ultra performance 
      liquid chromatography-tandem mass spectrometry with post-column ammoniation].
PG  - 1026-30
AB  - A method for the determination of cyanuric acid in milk and milk powder has been 
      developed by ultra performance liquid chromatography-tandem mass spectrometry 
      (UPLC-MS/MS) with post-column ammoniation. After extracted by 5% trichloroacetic 
      acid, the samples were loaded onto an Acquity UPLC HSS T3 column (50 mm x 2.1 mm, 
      1.8 microm) and separated with a gradient elution. The electrospray was operated 
      in the negative mode and monitored by the multiple reaction monitoring (MRM) 
      mode. The calibration curves showed a good linearity in the range of 10.0-160.0 
      microg/L, and the correlation coefficients (r) were higher than 0.99. When the 
      spiked levels were 0.05, 0.10, and 0.20 mg/kg, the recoveries of cyanuric acid in 
      milk ranged from 60% to 118.5%, with the relative standard deviations (RSDs) of 
      8.2%-12.6%; while the spiked levels were 0.25, 0.50, and 1.00 mg/kg in the milk 
      powder, the recoveries ranged from 88% to 108% and the RSDs ranged from 
      2.5%-5.7%. The limits of quantification (LOQs, S/N = 10) of cyanuric acid were 
      0.05 mg/kg in milk sample and 0.25 mg/kg in milk powder. The results indicate 
      that the method is simple, rapid, sensitive and suitable for the qualitative and 
      quantitative analyses of cyanuric acid in milk and milk powder samples.
FAU - Yun, Huan
AU  - Yun H
AD  - Technology Center of Beijing Entry-Exit Inspection and Quarantine Bureau, Beijing 
      100026, China. yunh@bjciq.gov.cn
FAU - Zhang, Zhaohui
AU  - Zhang Z
FAU - Gao, Yangyang
AU  - Gao Y
FAU - He, Yue
AU  - He Y
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Triazines)
RN  - H497R4QKTZ (cyanuric acid)
SB  - IM
MH  - Animals
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Contamination/analysis
MH  - Milk/*chemistry
MH  - Tandem Mass Spectrometry/*methods
MH  - Triazines/*analysis
EDAT- 2011/03/09 06:00
MHDA- 2012/02/14 06:00
CRDT- 2011/03/09 06:00
PHST- 2011/03/09 06:00 [entrez]
PHST- 2011/03/09 06:00 [pubmed]
PHST- 2012/02/14 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2010 Nov;28(11):1026-30.