PMID- 21391481
OWN - NLM
STAT- MEDLINE
DCOM- 20110407
LR  - 20190729
IS  - 1060-3271 (Print)
IS  - 1060-3271 (Linking)
VI  - 94
IP  - 1
DP  - 2011 Jan-Feb
TI  - Ultra high pressure liquid chromatography for crude plant extract profiling.
PG  - 51-70
AB  - Ultra high pressure liquid chromatography (UHPLC) systems operating at very high 
      pressures and using sub-2 microm packing columns have allowed a remarkable 
      decrease in analysis time and increase in peak capacity, sensitivity, and 
      reproducibility compared to conventional HPLC. This technology has rapidly been 
      widely accepted by the analytical community and is being gradually applied to 
      various fields of plant analysis such as QC, profiling and fingerprinting, 
      dereplication, and metabolomics. For many applications, an important improvement 
      of the overall performances has been reported. In this review, the basic 
      principles of UHPLC are summarized, and practical information on the type of 
      columns used and phase chemistry available is provided. An overview of the latest 
      applications to natural product analysis in complex mixtures is given, and the 
      potential and limitations as well as some new trends in the development of UHPLC 
      are discussed.
FAU - Eugster, Philippe J
AU  - Eugster PJ
AD  - School of Pharmaceutical Sciences, EPGL, University of Geneva, University of 
      Lausanne, 30, Quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.
FAU - Guillarme, Davy
AU  - Guillarme D
FAU - Rudaz, Serge
AU  - Rudaz S
FAU - Veuthey, Jean-Luc
AU  - Veuthey JL
FAU - Carrupt, Pierre-Alain
AU  - Carrupt PA
FAU - Wolfender, Jean-Luc
AU  - Wolfender JL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - J AOAC Int
JT  - Journal of AOAC International
JID - 9215446
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Arabidopsis/chemistry
MH  - Chromatography, High Pressure Liquid/instrumentation/*methods
MH  - Metabolomics
MH  - Panax/chemistry
MH  - Plant Extracts/*chemistry
MH  - Plants/chemistry/metabolism
EDAT- 2011/03/12 06:00
MHDA- 2011/04/08 06:00
CRDT- 2011/03/12 06:00
PHST- 2011/03/12 06:00 [entrez]
PHST- 2011/03/12 06:00 [pubmed]
PHST- 2011/04/08 06:00 [medline]
PST - ppublish
SO  - J AOAC Int. 2011 Jan-Feb;94(1):51-70.