PMID- 21396215 OWN - NLM STAT- MEDLINE DCOM- 20110629 LR - 20151119 IS - 1815-7920 (Electronic) IS - 1027-3719 (Linking) VI - 15 IP - 4 DP - 2011 Apr TI - High prevalence of asthma and atopy in the Canary Islands, Spain. PG - 536-41 LID - 10.5588/ijtld.10.0303 [doi] AB - OBJECTIVE: To evaluate the prevalence of and risk factors for asthma and related conditions in the Canaries, Spain. METHODS: From a randomised sample of 9506 adults aged 20-44 years who answered a short questionnaire, a random sample corresponding to 20% of the original was taken. Subjects classified as symptomatic in the previous survey and who were not included in the random sample were also invited to participate. The subjects completed a respiratory questionnaire, and underwent spirometry, bronchial hyperresponsiveness (BHR) test, skin tests and immunoglobulin E (IgE) measurements. RESULTS: The random sample included 593 subjects. The prevalence of skin sensitisation to mites was 30.3% (95%CI 26.7-34.2) and the prevalence of IgE to mites 30.5% (95%CI 26.2-35.2). A prevalence of 40.6% (95%CI 35.9-45.5) was found for atopy, 14.1% (95%CI 11.1-17.1) for BHR and 4.2% (95%CI, 2.5-5.9) for asthma. The risk factors most strongly associated with asthma were atopy (OR 4.89, 95%CI 3.07-7.78) and respiratory infection before the age of 5 years (OR 2.78, 95%CI 1.66-4.67). CONCLUSION: This study shows a high prevalence of sensitisation to mites, atopy, BHR and asthma in the Canaries, similar to that observed in English-speaking countries. We suggest that these findings could partially result from climatic conditions. FAU - Julia-Serda, G AU - Julia-Serda G AD - Servicio de Neumologia, Hospital Universitario Dr Negrin, Las Palmas de Gran Canaria, Spain. jjulser@gobiernodecanarias.org FAU - Cabrera-Navarro, P AU - Cabrera-Navarro P FAU - Acosta-Fernandez, O AU - Acosta-Fernandez O FAU - Martin-Perez, P AU - Martin-Perez P FAU - Losada-Cabrera, P AU - Losada-Cabrera P FAU - Garcia-Bello, M A AU - Garcia-Bello MA FAU - Carrillo-Diaz, T AU - Carrillo-Diaz T FAU - Anto-Boque, J AU - Anto-Boque J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - France TA - Int J Tuberc Lung Dis JT - The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease JID - 9706389 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Animals MH - Asthma/*epidemiology/immunology MH - Bronchial Hyperreactivity/*epidemiology MH - Climate MH - Humans MH - Hypersensitivity, Immediate/*epidemiology/immunology MH - Immunoglobulin E/*immunology MH - Prevalence MH - Pyroglyphidae/immunology MH - Risk Factors MH - Skin Tests/methods MH - Spain/epidemiology MH - Spirometry MH - Surveys and Questionnaires MH - Young Adult EDAT- 2011/03/15 06:00 MHDA- 2011/06/30 06:00 CRDT- 2011/03/15 06:00 PHST- 2011/03/15 06:00 [entrez] PHST- 2011/03/15 06:00 [pubmed] PHST- 2011/06/30 06:00 [medline] AID - 10.5588/ijtld.10.0303 [doi] PST - ppublish SO - Int J Tuberc Lung Dis. 2011 Apr;15(4):536-41. doi: 10.5588/ijtld.10.0303.